c-Rel 抗体
Quick Overview for c-Rel 抗体 (ABIN968997)
抗原
See all c-Rel 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- c-Rel Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human c-Rel expressed in E. Coli.
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亚型
- IgG1
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应用备注
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ELISA: 1/10000
ICC: 1/200 - 1/1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. ..." in: Gut, Vol. 58, Issue 8, pp. 1078-83, (2009) (PubMed).
: "Ser484 and Ser494 in REL are the major sites of IKK phosphorylation in vitro: evidence that IKK does not directly enhance GAL4-REL transactivation." in: Gene expression, Vol. 14, Issue 4, pp. 195-205, (2008) (PubMed).
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: "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling. ..." in: Gut, Vol. 58, Issue 8, pp. 1078-83, (2009) (PubMed).
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- c-Rel (REL proto-oncogene (c-Rel))
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别名
- c-Rel
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背景
- The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the 'Rel domain,' which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor.
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分子量
- 68.5 kDa
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基因ID
- 5966
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UniProt
- Q04864
抗原
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