ATF2 抗体
Quick Overview for ATF2 抗体 (ABIN968968)
抗原
See all ATF2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- ATF2 Antibody
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human ATF2 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- ELISA: 1/10000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma." in: Journal of dermatological science, Vol. 51, Issue 3, pp. 210-5, (2008) (PubMed).
: "Regulation of TIP60 by ATF2 modulates ATM activation." in: The Journal of biological chemistry, Vol. 283, Issue 25, pp. 17605-14, (2008) (PubMed).
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: "Overexpression of phosphorylated-ATF2 and STAT3 in cutaneous squamous cell carcinoma, Bowen's disease and basal cell carcinoma." in: Journal of dermatological science, Vol. 51, Issue 3, pp. 210-5, (2008) (PubMed).
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- ATF2 (Activating Transcription Factor 2 (ATF2))
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别名
- ATF2
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背景
- This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. The protein forms a homodimer or heterodimer with c-Jun and stimulates CRE-dependent transcription. The protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro, thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Additional transcript variants have been identified but their biological validity has not been determined.Tissue specificity: Abundant expression seen in the brain.
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分子量
- 55 kDa
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基因ID
- 1386
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UniProt
- P15336
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途径
- MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
抗原
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