SORL1 抗体 (AA 1220-1337)
(4 references)-
- 抗原 See all SORL1 抗体
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
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抗原表位
- AA 1220-1337
- 适用
- 人, 小鼠, 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SORL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF)
- 交叉反应
- 大鼠, 小鼠
- 产品特性
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1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
2. Please refer to us for technical protocols.
3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
4. Source of all serum proteins is from USDA inspected abattoirs located in the United States. - 纯化方法
- The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
- 免疫原
- Human LR11 aa. 1220-1337
- 克隆位点
- 48-LR11
- 亚型
- IgG2a
- Top Product
- Discover our top product SORL1 Primary Antibody
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anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) antibody
SORL1 适用: 人 ELISA, WB, IHC, ICC 宿主: 小鼠 Monoclonal 3B6B11 unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (C-Term) antibodyVerified SORL1 适用: 人 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 652-665), (Extracellular), (N-Term) antibodySORL1 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2001-2100) antibodySORL1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 82-181) antibodySORL1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3F2 unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2159-2214) antibodySORL1 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 7D7B11 unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 525-744) antibodySORL1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 82-181) antibodySORL1 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1) (AA 2065-2214) antibodySORL1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 说明
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Related Products: ABIN968545, ABIN967389
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 250 μg/mL
- 缓冲液
- Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store undiluted at -20°C.
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: "Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies." in: The Journal of comparative neurology, Vol. 511, Issue 2, pp. 238-56, (2008) (PubMed).
: "Uptake of lipoproteins for axonal growth of sympathetic neurons." in: The Journal of biological chemistry, Vol. 275, Issue 26, pp. 19883-90, (2000) (PubMed).
: "Molecular characterization of a novel human hybrid-type receptor that binds the alpha2-macroglobulin receptor-associated protein." in: The Journal of biological chemistry, Vol. 271, Issue 49, pp. 31379-83, (1997) (PubMed).
: "Elements of neural adhesion molecules and a yeast vacuolar protein sorting receptor are present in a novel mammalian low density lipoprotein receptor family member." in: The Journal of biological chemistry, Vol. 271, Issue 40, pp. 24761-8, (1996) (PubMed).
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: "Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies." in: The Journal of comparative neurology, Vol. 511, Issue 2, pp. 238-56, (2008) (PubMed).
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- 抗原
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
- 别名
- LR11 (SORL1 产品)
- 别名
- SORL1 antibody, C11orf32 antibody, LR11 antibody, LRP9 antibody, SORLA antibody, SorLA-1 antibody, gp250 antibody, SorLA antibody, 2900010L19Rik antibody, AI596264 antibody, AW261561 antibody, mSorLA antibody, Lr11 antibody, RGD619914 antibody, sortilin related receptor 1 antibody, sortilin-related receptor antibody, sortilin-related receptor, L(DLR class) A repeats containing antibody, sortilin-related receptor, L(DLR class) A repeats-containing antibody, sortilin-related receptor, LDLR class A repeats-containing antibody, sorl1 antibody, LOC582560 antibody, SORL1 antibody, Sorl1 antibody
- 背景
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The low-density lipoprotein receptor (LDLR) functions in lipoprotein transport pathways, and is involved in familial hypercholesterolemia. Homologues of the LDLR may have diverse functions and their ligands may include biological inactive plasma carrier complexes, plasma lipoproteins, yolk precursors, toxins, and extracellular lipoproteins. LR11 (also known as sorLA-1 and gp250) is a lipoprotein receptor homologue that contains 11 LDL receptor ligand binding repeats (LDLRs), 5 LDL receptor YWTDrepeats, a large fibronectin-type III (FIII) hexarepeat domain similar to neural adhesion proteins, and a domain with similarity to the yeast receptor for vacuolar protein sorting (Vsp10p). LR11mRNA is expressed at high levels in brain, but is also found in liver, pancreas, adrenal gland, and testis. LR11 can bind the ER and Golgi localized receptor associated protein (RAP), which binds to many members of the LDLR family and prevents aggregation of ligands to the LDLRs. In addition, LR11 binds apolipoprotein E-containing lipoproteins. Thus, LR11 is a lipoprotein binding receptor that may have additional functions related to protein sorting and neuronal development.
Synonyms: SorLA, gp250, Lipoprotein Receptor-11 - 分子量
- 250 kDa
- 途径
- Smooth Muscle Cell Migration
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