SORL1 抗体 (AA 2159-2214)
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- 抗原 See all SORL1 抗体
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
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抗原表位
- AA 2159-2214
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This SORL1 antibody is un-conjugated
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应用范围
- ELISA, Western Blotting (WB)
- 纯化方法
- purified
- 免疫原
- Purified recombinant fragment of SORL1 (aa2159-2214) expressed in E. coli.
- 克隆位点
- 7D7B11
- 亚型
- IgG1
- Top Product
- Discover our top product SORL1 Primary Antibody
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- 应用备注
- ELISA: 1:10000, WB: 1:500 - 1:2000
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- Ascitic fluid containing 0.03 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- 4°C, -20°C for long term storage
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sorLA: sorting out APP." in: Molecular interventions, Vol. 6, Issue 2, pp. 74-6, 58, (2006) (PubMed).
: "Evaluation of reference genes for studies of gene expression in human adipose tissue." in: Obesity research, Vol. 13, Issue 4, pp. 649-52, (2005) (PubMed).
: "Loss of apolipoprotein E receptor LR11 in Alzheimer disease." in: Archives of neurology, Vol. 61, Issue 8, pp. 1200-5, (2004) (PubMed).
: "
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sorLA: sorting out APP." in: Molecular interventions, Vol. 6, Issue 2, pp. 74-6, 58, (2006) (PubMed).
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- 抗原
- SORL1 (Sortilin-Related Receptor, L(DLR Class) A Repeats Containing (SORL1))
- 别名
- SORL1 (SORL1 产品)
- 别名
- SORL1 antibody, C11orf32 antibody, LR11 antibody, LRP9 antibody, SORLA antibody, SorLA-1 antibody, gp250 antibody, SorLA antibody, 2900010L19Rik antibody, AI596264 antibody, AW261561 antibody, mSorLA antibody, Lr11 antibody, RGD619914 antibody, sortilin related receptor 1 antibody, sortilin-related receptor antibody, sortilin-related receptor, L(DLR class) A repeats containing antibody, sortilin-related receptor, L(DLR class) A repeats-containing antibody, sortilin-related receptor, LDLR class A repeats-containing antibody, sorl1 antibody, LOC582560 antibody, SORL1 antibody, Sorl1 antibody
- 背景
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Description: SORL1 (sortilin-related receptor, L A repeats containing) also known as sorting protein-related receptor containing LDLR class A (SorLA), is a Type I membrane protein that may be involved in cell-cell interaction. SorLA, a single transmembrane receptor, binds LDL and transports it into cells by endocytosis. SorLA is synthesized as a proreceptor which is processed to the mature form by a furin-like propeptidase. It can also bind to RAP (receptor-associated protein). SorLA is a multifunctional endocytis receptor important in lipoprotein and protease uptake. The N-terminal propeptide, which is removed, can be cleaved by furin or homologous proteases. Endogenous SorLA binds the neuropeptide head activator (HA) and is important for HA signaling and function. The gene encoding for the protein maps to chromosome 8p23.1. SorLA is expressed mainly in brain (cerebral cortex, cerebellum and the occipital pole), but can also be found in liver, spinal cord, kidney, testis and pancreas.
Aliases: SORL1
- 基因ID
- 6653
- HGNC
- 6653
- 途径
- Smooth Muscle Cell Migration
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