(2 references)-
- 抗原 See all PAX8 抗体
- PAX8 (Paired Box 8 (PAX8))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This PAX8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human PAX8 expressed in E. Coli.
- 克隆位点
- 2D4
- 亚型
- IgG1
- Top Product
- Discover our top product PAX8 Primary Antibody
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anti-Paired Box 8 (PAX8) antibody
KO Validated PAX8 适用: 人 WB, IHC, IF, IHC (p), IP, ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal PAX8-1492 unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1A1D3 unconjugated
anti-Paired Box 8 (PAX8) (AA 60-261) antibodyPAX8 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal PAX8-1491 unconjugated
anti-Paired Box 8 (PAX8) (AA 1-450) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3H7 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2D6 unconjugated
anti-Paired Box 8 (PAX8) (AA 300-377) antibodyPAX8 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G11 unconjugated
anti-Paired Box 8 (PAX8) (AA 141-250) antibodyPAX8 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F1 unconjugated
anti-Paired Box 8 (PAX8) (N-Term) antibodyVerified PAX8 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Paired Box 8 (PAX8) (AA 300-450) antibodyPAX8 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3E6B3 unconjugated
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." in: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).
: "Fluorescence in situ hybridization analysis using PAX8- and PPARG-specific probes reveals the presence of PAX8-PPARG translocation and 3p25 aneusomy in follicular thyroid neoplasms." in: Cancer genetics and cytogenetics, Vol. 196, Issue 1, pp. 7-13, (2009) (PubMed).
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: "Utility of paired box gene 8 (PAX8) expression in fluid and fine-needle aspiration cytology: an immunohistochemical study of metastatic ovarian serous carcinoma." in: Cancer cytopathology, Vol. 118, Issue 5, pp. 298-302, (2010) (PubMed).
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- 抗原
- PAX8 (Paired Box 8 (PAX8))
- 别名
- PAX8 (PAX8 产品)
- 别名
- PAX8 antibody, XPax-8 antibody, XPax8 antibody, pax-8 antibody, PAX-8 antibody, Pax-8 antibody, paired box 8 antibody, paired box 8 L homeolog antibody, PAX8 antibody, pax8 antibody, Pax8 antibody, pax8.L antibody
- 背景
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This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas.
Tissue specificity: Expressed in the excretory system, thyroid gland and Wilms tumors.ABCAM: This protein is a member of the paired box (PAX) family of transcription factors, typically containing a paired box domain, an octapeptide, and a paired-type homeodomain. This family plays critical roles during fetal development and cancer growth. The specific function of the PAX8 is unknown but it may involve kidney cell differentiation, thyroid development, or thyroid dysgenesis. Alternative splicing in the gene by inclusion or exclusion of exons 7 and/or 8 has produced several known products but the biological significance of the variants is unknown. Several other splice variants have been proposed but the full nature of these products has not been described. Pax8 is also a marker of otic progenitor cells.
Synonyms: PAX8 - 分子量
- 60kDa
- 基因ID
- 7846
- 途径
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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