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N-Cadherin 抗体 (Middle Region)

CDH2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN966637
发货至: 中国
  • 抗原 See all N-Cadherin (CDH2) 抗体
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    抗原表位
    • 22
    • 15
    • 14
    • 10
    • 6
    • 6
    • 4
    • 3
    • 3
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    Middle Region
    适用
    • 134
    • 96
    • 68
    • 21
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    • 4
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    • 3
    • 3
    • 3
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    宿主
    • 88
    • 55
    • 4
    • 4
    • 3
    克隆类型
    • 81
    • 73
    多克隆
    标记
    • 88
    • 16
    • 5
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    This N-Cadherin antibody is un-conjugated
    应用范围
    • 120
    • 58
    • 42
    • 40
    • 31
    • 23
    • 18
    • 15
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠, 大鼠
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Cadherin-2 (CDH2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human N-Cadherin, identical to the related rat and mouse sequences.< br/>Immunogen was affinity purified.
    亚型
    IgG
    Top Product
    Discover our top product CDH2 Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 µg/mL.
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Sodium azide, Thimerosal (Merthiolate)
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    At -20 °C for one year. After reconstitution, at 4 °C for one month. It can also be aliquotted and stored frozen at -20 °C for a longer time.
  • Togashi, Abe, Mizoguchi, Takaoka, Chisaka, Takeichi: "Cadherin regulates dendritic spine morphogenesis." in: Neuron, Vol. 35, Issue 1, pp. 77-89, (2002) (PubMed).

    Miyatani, Copeland, Gilbert, Jenkins, Takeichi: "Genomic structure and chromosomal mapping of the mouse N-cadherin gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 18, pp. 8443-7, (1992) (PubMed).

    Walsh, Barton, Putt, Moore, Kelsell, Spurr, Goodfellow: "N-cadherin gene maps to human chromosome 18 and is not linked to the E-cadherin gene." in: Journal of neurochemistry, Vol. 55, Issue 3, pp. 805-12, (1990) (PubMed).

  • 抗原
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    别名
    Cadherin-2 (CDH2 产品)
    别名
    CD325 antibody, CDHN antibody, CDw325 antibody, NCAD antibody, N-cadherin antibody, cadherin-2 antibody, cdhn antibody, ncad antibody, cdw325 antibody, CDH2 antibody, Cadherin-2 antibody, Ncad antibody, glo antibody, lyr antibody, pac antibody, wu:fb47h04 antibody, cadherin 2 antibody, cadherin 2 S homeolog antibody, cadherin 2, type 1, N-cadherin (neuronal) antibody, CDH2 antibody, cdh2.S antibody, cdh2 antibody, Cdh2 antibody
    背景
    N-cadherin (NCAD) is a member of the cadherin cell-cell adhesion receptor family that includes P-, E-, and R-cadherin and liver cell adhesion molecule (L-CAM). N-Cadherin, also known as Cadherin-2, encodes a 907-amino acid protein that includes a 159-amino acid signal sequence. Human and mouse nucleotide sequences are 96 % identical. Mouse Ncad gene consists of 16 exons dispersed over more than 200 kb of genomic DNA. Human N-cadherin gene contains 16 exons and its sequence is highly similar to both the mouse NCAD gene (including the large first and second introns) and other cadherin genes. N-cadherin is mapped to 18q11. 2. Cadherin regulates dendritic spine morphogenesis.
    途径
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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