MEK1 抗体
Our Local Distributor
北京 101111
Quick Overview for MEK1 抗体 (ABIN966564)
抗原
See all MEK1 (MAP2K1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
特异性
- MEK1 (Ab-291) antibody detects endogenous levels of total MEK1 protein.
-
纯化方法
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
-
免疫原
- The antiserum was produced against synthesized non-phosphopeptide derived from human MEK1 around the phosphorylation site of threonine 291 (P-R-TP-P-G).
-
-
-
-
应用备注
-
WB: 1:500~1:1000
IHC: 1:50~1:100. -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 100ug/100ul.
-
缓冲液
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- -20 °C
-
-
-
: "Phosphatidylinositol 3-kinase and mek1/2 are necessary for insulin-like growth factor-I-induced vascular endothelial growth factor synthesis in prostate epithelial cells: a role for hypoxia-inducible ..." in: Molecular cancer research : MCR, Vol. 1, Issue 4, pp. 312-22, (2003) (PubMed).
: "Loss of active MEK1-ERK1/2 restores epithelial phenotype and morphogenesis in transdifferentiated MDCK cells." in: American journal of physiology. Cell physiology, Vol. 285, Issue 3, pp. C652-61, (2003) (PubMed).
: "Requirement for a hsp90 chaperone-dependent MEK1/2-ERK pathway for B cell antigen receptor-induced cyclin D2 expression in mature B lymphocytes." in: The Journal of biological chemistry, Vol. 277, Issue 14, pp. 12144-50, (2002) (PubMed).
: "Superantigen-induced T cell:B cell conjugation is mediated by LFA-1 and requires signaling through Lck, but not ZAP-70." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 167, Issue 10, pp. 5708-18, (2001) (PubMed).
-
-
- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
-
别名
- MEK1
-
途径
- MAPK Pathway, RTK signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
抗原
-