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- 抗原 See all FLT4 抗体
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This FLT4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human FLT4 expressed in E. Coli.
- 克隆位点
- 4H4
- 亚型
- IgG1
- Top Product
- Discover our top product FLT4 Primary Antibody
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- 应用备注
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Western Bloting: 1/500 - 1/2000.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications.
Determining optimal working dilutions by titration test. - 限制
- 仅限研究用
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- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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The cost of non-compliance in congenital adrenal hyperplasia." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 22, Issue 12, pp. 1093-4, (2010) (PubMed).
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The cost of non-compliance in congenital adrenal hyperplasia." in: Journal of pediatric endocrinology & metabolism : JPEM, Vol. 22, Issue 12, pp. 1093-4, (2010) (PubMed).
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- 抗原
- FLT4 (Fms-Related Tyrosine Kinase 4 (FLT4))
- 别名
- FLT4 (FLT4 产品)
- 别名
- FLT41 antibody, LMPH1A antibody, PCL antibody, VEGFR3 antibody, AI323512 antibody, Chy antibody, Flt-4 antibody, VEGFR-3 antibody, Vegfr3 antibody, cb1059 antibody, fms related tyrosine kinase 4 antibody, FMS-like tyrosine kinase 4 antibody, fms-related tyrosine kinase 4 antibody, FLT4 antibody, Flt4 antibody, flt4 antibody
- 背景
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This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA.
Tissue specificity: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain. VEGFR-3 is induced in all endothelial cells (ECis) during early embryogenesis, and its expression eventually disappears from the vascular endothelial cells of adult tissues. VEGFR-3 is constitutively expressed in the adult lymphatic endothelium. Although VEGFR-3 is not expressed in adult blood vessels, it is induced in vascular endothelial cells of tumor-bearing tissues.VEGFR-3 expression in adults is largely restricted to the endothelial cells of the lymphatic system, and high endothelial venules (HEV).
Synonyms: PCL, FLT41, LMPH1A, VEGFR3, FLT4 - 分子量
- 145kDa
- 基因ID
- 2324
- 途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGF Signaling
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