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DDC 抗体 (C-Term)

DDC 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965981
发货至: 中国
  • 抗原 See all DDC 抗体
    DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
    抗原表位
    • 15
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    • 1
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    C-Term
    适用
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    宿主
    • 61
    • 10
    • 2
    • 2
    克隆类型
    • 59
    • 16
    多克隆
    标记
    • 39
    • 6
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    This DDC antibody is un-conjugated
    应用范围
    • 60
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    • 16
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    Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-specific affinity chromatography.
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to C-terminal residues of human DDC (Netrin receptor DCC precursor) (Tumor suppressor protein DCC)
    Top Product
    Discover our top product DDC Primary Antibody
  • 应用备注
    ELISA, Western blotting: 1µg/ml for 2hrs.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    This antibody is stored in PBS, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))
    别名
    DDC (DDC 产品)
    别名
    AADC antibody, wu:fa56d05 antibody, wu:fd59h03 antibody, wu:fk20h01 antibody, zgc:65801 antibody, zgc:76929 antibody, Ddc antibody, DdcDv antibody, Dvir\\GJ17995 antibody, GJ17995 antibody, dvir_GLEANR_2561 antibody, Aadc antibody, 5-HT antibody, CG10697 antibody, DDC antibody, DdcDm antibody, Dmel\\CG10697 antibody, ddc antibody, fDDC antibody, l(2)37Bl antibody, l(2)37Ch antibody, l(2)k02104 antibody, dopa decarboxylase antibody, Dopa-decarboxylase antibody, dopa decarboxylase (aromatic L-amino acid decarboxylase) antibody, Dopa decarboxylase antibody, dopa decarboxylase L homeolog antibody, DDC antibody, ddc antibody, Ddc antibody, Dvir\Ddc antibody, ddc.L antibody
    背景
    DDC (Netrin receptor DCC) (Tumor suppressor protein DCC) is a receptor for netrin required for axon guidance. It mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. The protein implicated as a tumor suppressor gene. It interacts with the cytoplasmic part of UNC5A, UNC5B, UNC5C and probably UNC5D (By similarity). Colorectal tumors that lost their capacity to differentiate into mucus producing cells uniformly lack DCC expression. Inactivation of DCC due to allelic deletion and/or point mutations may cause both lymphatic and hematogenous metastasis of esophageal squamous cell carcinomas.
    途径
    Dopaminergic Neurogenesis
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