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DDC 抗体 (N-Term)

There is 1 publication for this product available. The 兔 多克隆 anti-DDC antibody is suitable to detect DDC in samples from 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马 和 斑马鱼. It has been validated for WB 和 IHC.
产品编号 ABIN2776802
发货至: 中国
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Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for DDC 抗体 (N-Term) (ABIN2776802)

抗原

See all DDC 抗体
DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 兔, 马, 斑马鱼

宿主

  • 81
  • 10
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兔

克隆类型

  • 78
  • 17
多克隆

标记

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This DDC antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    DDC Antibody - N-terminal region

    序列

    EFRRRGKEMV DYVANYMEGI EGRQVYPDVE PGYLRPLIPA AAPQEPDTFE

    预测反应

    Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 92%, Zebrafish: 92%

    产品特性

    This is a rabbit polyclonal antibody against DDC. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human DDC
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    说明

    We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41425-100UG

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.0 mg/mL

    缓冲液

    Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    prevent freeze-thaw cycles

    储存条件

    4 °C,-20 °C

    储存方法

    For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
  • Shimohata, Ishihara, Hattori, Miyamoto, Morishita, Ornthanalai, Raveau, Ebrahim, Amano, Yamada, Sago, Akiba, Mataga, Murphy, Miyakawa, Yamakawa: "Ts1Cje Down syndrome model mice exhibit environmental stimuli-triggered locomotor hyperactivity and sociability concurrent with increased flux through central dopamine and serotonin metabolism." in: Experimental neurology, Vol. 293, pp. 1-12, (2017) (PubMed).

  • 抗原

    DDC (Dopa Decarboxylase (Aromatic L-Amino Acid Decarboxylase) (DDC))

    别名

    DDC

    背景

    Background Information: DDC catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine.

    Gene Name: Dopa decarboxylase (aromatic L-amino acid decarboxylase)

    Alternative Symbols: AADC

    Protein Name: Aromatic-L-amino-acid decarboxylase

    分子量

    53kDa

    基因ID

    1644

    NCBI登录号

    NP_000781

    UniProt

    P20711

    途径

    Dopaminergic Neurogenesis
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