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CST3 抗体

CST3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 5H2 unconjugated
产品编号 ABIN965940
发货至: 中国
  • 抗原 See all CST3 抗体
    CST3 (Cystatin C (CST3))
    适用
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CST3 antibody is un-conjugated
    应用范围
    • 102
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    Western Blotting (WB), ELISA
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CST3 expressed in E. Coli.
    克隆位点
    5H2
    亚型
    IgG1
    Top Product
    Discover our top product CST3 Primary Antibody
  • 应用备注
    Western Bloting: 1/500 - 1/2000.
    ELISA: Propose dilution 1/10000.
    Not yet tested in other applications.
    Determining optimal working dilutions by titration test.
    限制
    仅限研究用
  • 状态
    Liquid
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • Helisalmi, Väkevä, Hiltunen, Soininen: "Flanking markers of cystatin c (CST3) gene do not show association with Alzheimer's disease." in: Dementia and geriatric cognitive disorders, Vol. 27, Issue 4, pp. 318-21, (2009) (PubMed).

    Aubin, Labelle, Chevrefils, Desroches, Clin, Eng: "Preoperative planning simulator for spinal deformity surgeries." in: Spine, Vol. 33, Issue 20, pp. 2143-52, (2008) (PubMed).

  • 抗原
    CST3 (Cystatin C (CST3))
    别名
    CST3 (CST3 产品)
    别名
    armd11 antibody, fb51d07 antibody, wu:fb24g06 antibody, wu:fb51d07 antibody, wu:fc55f03 antibody, zgc:136227 antibody, ARMD11 antibody, CysC antibody, CYSC antibody, cystatin C antibody, cystatin C L homeolog antibody, cystatin C (amyloid angiopathy and cerebral hemorrhage) antibody, cystatin 3 antibody, CST3 antibody, cst3.L antibody, cst3 antibody, cystatin 3 antibody, Cst3 antibody
    背景
    The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.
    Tissue specificity: Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
    Synonyms: ARMD11, MGC117328, CST3
    分子量
    42kDa
    基因ID
    1471
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