(2 references)-
- 抗原 See all BPTF 抗体
- BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This BPTF antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human BLNK expressed in E. Coli.
- 克隆位点
- 2F10
- 亚型
- IgG1
- Top Product
- Discover our top product BPTF Primary Antibody
-
anti-Bromodomain PHD Finger Transcription Factor (BPTF) (AA 2801-3046) antibody
BPTF 适用: 小鼠, 大鼠 WB, IF (cc), IF (p), ELISA, IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Bromodomain PHD Finger Transcription Factor (BPTF) antibodyBPTF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-Bromodomain PHD Finger Transcription Factor (BPTF) antibodyBPTF 适用: 人 IHC (p), IF 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
Western Bloting: 1/500 - 1/2000.
Immunohistochemistry: 1/200 - 1/1000.
Immunofluorescence: 1/200 - 1/1000.
Flow cytometry: 1/200 - 1/400.
ELISA: Propose dilution 1/10000.
Not yet tested in other applications. Determinine optimal working dilutions by titration test. - 限制
- 仅限研究用
-
- 状态
- Liquid
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
-
-
: "BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9804-13, (2009) (PubMed).
: "B-cell linker protein prevents aneuploidy by inhibiting cytokinesis." in: Cancer science, Vol. 99, Issue 12, pp. 2444-54, (2008) (PubMed).
-
: "BLNK binds active H-Ras to promote B cell receptor-mediated capping and ERK activation." in: The Journal of biological chemistry, Vol. 284, Issue 15, pp. 9804-13, (2009) (PubMed).
-
- 抗原
- BPTF (Bromodomain PHD Finger Transcription Factor (BPTF))
- 别名
- BPTF (BPTF 产品)
- 别名
- FAC1 antibody, FALZ antibody, NURF301 antibody, 9430093H17Rik antibody, Falz antibody, BPTF antibody, bromodomain PHD finger transcription factor antibody, nucleosome-remodeling factor subunit NURF301 antibody, fetal alzheimer antigen, falz antibody, BPTF antibody, Bptf antibody, LOC5576547 antibody, CpipJ_CPIJ011285 antibody, bptf antibody
- 背景
-
This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: AGM4, BASH, LY57, SLP65, BLNKS, SLP-65, MGC111051 - 分子量
- 68kDa
- 基因ID
- 2186
-
You are here:
