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ATF2 抗体

This anti-ATF2 antibody is a 兔 多克隆 antibody detecting ATF2 in IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 5+ publications.
产品编号 ABIN965613
发货至: 中国

Quick Overview for ATF2 抗体 (ABIN965613)

抗原

See all ATF2 抗体
ATF2 (Activating Transcription Factor 2 (ATF2))

适用

  • 304
  • 235
  • 201
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  • 12
  • 11
  • 8
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  • 7
  • 5
  • 5
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  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 332
  • 15
  • 2
  • 1

克隆类型

  • 320
  • 30
多克隆

标记

  • 164
  • 18
  • 11
  • 11
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 9
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 3
  • 2
This ATF2 antibody is un-conjugated

应用范围

  • 253
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  • 119
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  • 87
  • 64
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  • 42
  • 30
  • 19
  • 15
  • 10
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  • 2
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  • 1
Immunohistochemistry (IHC)
  • 特异性

    ATF-2(Ab-71or 53) antibody detects endogenous levels of total ATF-2 protein.

    纯化方法

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    免疫原

    The antiserum was produced against synthesized non-phosphopeptide derived from human ATF-2 around the phosphorylation site of threonine 71 or 53 (T-P-TP-P-T).
  • 应用备注

    WB: 1:500~1:1000
    IHC: 1:50~1:100.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100ug/100ul

    缓冲液

    Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 50% glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C
  • Sevilla, Santos, Vega, Lazo: "Human vaccinia-related kinase 1 (VRK1) activates the ATF2 transcriptional activity by novel phosphorylation on Thr-73 and Ser-62 and cooperates with JNK." in: The Journal of biological chemistry, Vol. 279, Issue 26, pp. 27458-65, (2004) (PubMed).

    Waetzig, Seegert, Rosenstiel, Nikolaus, Schreiber: "p38 mitogen-activated protein kinase is activated and linked to TNF-alpha signaling in inflammatory bowel disease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 168, Issue 10, pp. 5342-51, (2002) (PubMed).

    Gupta, Campbell, Dérijard, Davis: "Transcription factor ATF2 regulation by the JNK signal transduction pathway." in: Science (New York, N.Y.), Vol. 267, Issue 5196, pp. 389-93, (1995) (PubMed).

    van Dam, Wilhelm, Herr, Steffen, Herrlich, Angel: "ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents." in: The EMBO journal, Vol. 14, Issue 8, pp. 1798-811, (1995) (PubMed).

    Abdel-Hafiz, Heasley, Kyriakis, Avruch, Kroll, Johnson, Hoeffler: "Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases." in: Molecular endocrinology (Baltimore, Md.), Vol. 6, Issue 12, pp. 2079-89, (1993) (PubMed).

  • 抗原

    ATF2 (Activating Transcription Factor 2 (ATF2))

    别名

    ATF2

    途径

    MAPK Pathway, RTK signaling, Thyroid Hormone Synthesis, Activation of Innate immune Response, Chromatin Binding, Myometrial Relaxation and Contraction, Synaptic Membrane, Tube Formation, Toll-Like Receptors Cascades
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