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AIF 抗体
AIFM1
适用: 人, 小鼠, 大鼠, 猴
WB, ELISA
宿主: 小鼠
Monoclonal
4E7
unconjugated
AIF抗体详情
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抗原
See all AIF (AIFM1) 抗体
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
适用
All reactivities for AIF 抗体
人, 小鼠, 大鼠, 猴
宿主
All hosts for AIF 抗体
小鼠
克隆类型
All clonalities for AIF 抗体
单克隆
标记
All conjugates for AIF 抗体
This AIF antibody is un-conjugated
应用范围
All applications for AIF 抗体
Western Blotting (WB), ELISA
纯化方法
Ascitic fluid
免疫原
Purified recombinant fragment of human AIF expressed in E. Coli.
克隆位点
4E7
Top Product
Discover our top product AIFM1 Primary Antibody
Alternatives
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anti-Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1) (AA 131-230) antibody
AIFM1
适用: 人, 小鼠, 大鼠, Pig
WB, ELISA, IHC (p), ICC, IF (cc), IF (p), IHC (fro)
宿主: 兔
Polyclonal
unconjugated
使用细节
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应用备注
Western Bloting: 1/500 - 1/2000. Immunohistochemistry: 1/200 - 1/1000. Immunofluorescence: 1/200 - 1/1000. Flow cytometry: 1/200 - 1/400. ELISA: Propose dilution 1/10000. Not yet tested in other applications. Determining optimal working dilutions by titration test.
限制
仅限研究用
贮存及处理
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状态
Liquid
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
储存条件
4 °C
AIF目标详情
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抗原
AIF (AIFM1)
(Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
别名
AIF (AIFM1 产品 )
别名
AIF antibody, CMTX4 antibody, COWCK antibody, COXPD6 antibody, PDCD8 antibody, CG7263 antibody, DmAIF antibody, Dmel\\CG7263 antibody, GB16024 antibody, DDBDRAFT_0187853 antibody, DDBDRAFT_0191137 antibody, DDB_0187853 antibody, DDB_0191137 antibody, aif antibody, pdcd8 antibody, AIFM1 antibody, PCD8 antibody, AIFsh2 antibody, Hq antibody, Pdcd8 antibody, mAIF antibody, Aif antibody, zgc:91994 antibody, apoptosis inducing factor mitochondria associated 1 antibody, allograft inflammatory factor 1 antibody, Apoptosis inducing factor antibody, apoptosis-inducing factor 1, mitochondrial antibody, apoptosis inducing factor antibody, apoptosis inducing factor, mitochondria associated 1 antibody, apoptosis-inducing factor, mitochondrion-associated, 1 antibody, apoptosis-inducing factor, mitochondrion-associated 1 antibody, AIFM1 antibody, AIF1 antibody, AIF antibody, LOC412212 antibody, aif antibody, aifm1 antibody, Aifm1 antibody
背景
This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells, and it is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it affects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Mutations in this gene cause combined oxidative phosphorylation deficiency 6, which results in a severe mitochondrial encephalomyopathy. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 10
基因ID
9131
途径
Apoptosis , Positive Regulation of Endopeptidase Activity , Cell RedoxHomeostasis , Smooth Muscle Cell Migration , Warburg Effect
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