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ACE2 抗体 (N-Term)

ACE2 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN965500
发货至: 中国
  • 抗原 See all ACE2 抗体
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    抗原表位
    • 16
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    N-Term
    适用
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    人, 小鼠
    宿主
    • 114
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    • 6
    克隆类型
    • 103
    • 36
    多克隆
    标记
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    This ACE2 antibody is un-conjugated
    应用范围
    • 115
    • 65
    • 50
    • 36
    • 30
    • 19
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    • 10
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    Immunohistochemistry (IHC)
    纯化方法
    Purified by antigen-specific affinity chromatography.
    免疫原
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of mouse Ace2 protein
    Top Product
    Discover our top product ACE2 Primary Antibody
  • 应用备注
    ELISA, Western blotting: 1µg/ml for 2hrs.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    This antibody is stored in PBS, 50% glycerol
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    ACE2 (Angiotensin I Converting Enzyme 2 (ACE2))
    别名
    Ace2 (ACE2 产品)
    别名
    ACE1 antibody, CD143 antibody, DCP antibody, DCP1 antibody, ICH antibody, MVCD3 antibody, ACEH antibody, 2010305L05Rik antibody, zgc:92514 antibody, angiotensin I converting enzyme antibody, angiotensin I converting enzyme 2 antibody, angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 antibody, ACE antibody, ACE2 antibody, Ace2 antibody, ace2 antibody
    背景
    Ace2(Angiotensin-converting enzyme 2) is an ACErelated carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Ace2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. It may be an important regulator of heart function. Ace2 may have a protective role in acute lung injury. Ace2 binds 1 zinc ion per subunit and 1 chloride ion per subunit. Mice lacking ACE2 are viable and fertile, exhibit normal kidney and lung function, but show a severe reduction in cardiac contractility, and are highly sensitive to severe acute lung failure. Transgenic mice overexpressing ACE2 in the heart appear healthy but show conduction disturbances and ventricular arrhythmias which can lead to sudden death. Angiotensin-converting enzyme 2 is an essential regulator of heart function
    途径
    ACE Inhibitor Pathway, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Feeding Behaviour
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