KAT2B 抗体 (C-Term)
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Quick Overview for KAT2B 抗体 (C-Term) (ABIN954021)
抗原
See all KAT2B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 802-832, C-Term
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特异性
- This antibody reacts to PCAF.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Saturated Ammonium Sulfate (SAS) precipitation
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免疫原
- KLH conjugated synthetic peptide between 802-832 amino acids from the C-terminal region of human PCAF
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亚型
- Ig Fraction
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.25 mg/mL
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缓冲液
- PBS, 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
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别名
- PCAF / KAT2B
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背景
- CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.Synonyms: Histone acetylase PCAF, Histone acetyltransferase KAT2B, Histone acetyltransferase PCAF, Lysine acetyltransferase 2B, P/CAF, P300/CBP-associated factor
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分子量
- 93013 Da
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基因ID
- 8850
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NCBI登录号
- NP_003875
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途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
抗原
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