电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KAT2B 抗体 (C-Term)

KAT2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2856697
发货至: 中国
  • 抗原 See all KAT2B 抗体
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    抗原表位
    • 16
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 72
    • 32
    • 25
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠
    宿主
    • 60
    • 12
    克隆类型
    • 52
    • 20
    多克隆
    标记
    • 46
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KAT2B antibody is un-conjugated
    应用范围
    • 56
    • 30
    • 16
    • 14
    • 13
    • 8
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    交叉反应
    斑马鱼
    交叉反应 (详细)
    Zebrafish (88 %)
    产品特性
    Rabbit Polyclonal antibody to PCAF (K(lysine) acetyltransferase 2B)
    PCAF antibody [C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PCAF. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product KAT2B Primary Antibody
  • 应用备注
    Suggested dilution Reference Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceWestern blot1:500-1:3000*
    说明

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , mouse brain , *MFB

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Sengupta, Yang, Hegde, Hegde, Mitra, Pandey, Dutta, Datarwala, Bhakat, Mitra: "Acetylation of oxidized base repair-initiating NEIL1 DNA glycosylase required for chromatin-bound repair complex formation in the human genome increases cellular resistance to oxidative stress." in: DNA repair, Vol. 66-67, pp. 1-10, (2018) (PubMed).

    Cazzalini, Sommatis, Tillhon, Dutto, Bachi, Rapp, Nardo, Scovassi, Necchi, Cardoso, Stivala, Prosperi: "CBP and p300 acetylate PCNA to link its degradation with nucleotide excision repair synthesis." in: Nucleic acids research, Vol. 42, Issue 13, pp. 8433-48, (2014) (PubMed).

  • 抗原
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    别名
    PCAF (KAT2B 产品)
    别名
    PCAF antibody, pcaf antibody, si:ch211-1j13.2 antibody, zgc:161980 antibody, gb:dq017634 antibody, im:7156024 antibody, CAF antibody, P antibody, P/CAF antibody, A930006P13Rik antibody, AI461839 antibody, AW536563 antibody, Pcaf antibody, p/CAF antibody, lysine acetyltransferase 2B antibody, K(lysine) acetyltransferase 2B antibody, K(lysine) acetyltransferase 2A antibody, KAT2B antibody, kat2b antibody, kat2a antibody, Kat2b antibody
    背景
    CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.

    Cellular Localization: Nucleus
    分子量
    93 kDa
    基因ID
    8850
    途径
    p53 Pathway, Regulation of Carbohydrate Metabolic Process
You are here:
客服