KAT2B 抗体 (AA 451-550)
-
- 抗原 See all KAT2B 抗体
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
-
抗原表位
- AA 451-550
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This KAT2B antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 大鼠
- 预测反应
- Mouse,Dog,Pig,Horse,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human KAT2B
- 亚型
- IgG
- Top Product
- Discover our top product KAT2B Primary Antibody
-
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibody
KAT2B 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 1H2 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 5E5 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 1-142) antibodyKAT2B 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, FACS, ICC, Neut 宿主: 小鼠 Monoclonal 7D12C8 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 353-452) antibodyKAT2B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2B4 unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (acLys428) antibodyKAT2B 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (AA 583-832) antibodyKAT2B 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-K(lysine) Acetyltransferase 2B (KAT2B) (C-Term) antibodyKAT2B 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
- 别名
- Kat2b (KAT2B 产品)
- 别名
- PCAF antibody, pcaf antibody, si:ch211-1j13.2 antibody, zgc:161980 antibody, gb:dq017634 antibody, im:7156024 antibody, CAF antibody, P antibody, P/CAF antibody, A930006P13Rik antibody, AI461839 antibody, AW536563 antibody, Pcaf antibody, p/CAF antibody, lysine acetyltransferase 2B antibody, K(lysine) acetyltransferase 2B antibody, K(lysine) acetyltransferase 2A antibody, KAT2B antibody, kat2b antibody, kat2a antibody, Kat2b antibody
- 背景
-
Synonyms: HYRC, p350, DNAPK, DNPK1, HYRC1, IMD26, XRCC7, DNA-PKcs, DNA-dependent protein kinase catalytic subunit, DNA-PK catalytic subunit, p460, PRKDC
Background: Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate p53/TP53 in the presence of supercoiled DNA is dependent on C1D. Contributes to the determination of the circadian period length by antagonizing phosphorylation of CRY1 'Ser-588' and increasing CRY1 protein stability, most likely through an indirect machanism. Interacts with CRY1 and CRY2, negatively regulates CRY1 phosphorylation.
- 基因ID
- 5591
- UniProt
- P78527
- 途径
- p53 Pathway, Regulation of Carbohydrate Metabolic Process
-
