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KAT2B 抗体 (C-Term)

KAT2B 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6264062
发货至: 中国
  • 抗原 See all KAT2B 抗体
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    抗原表位
    • 16
    • 9
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 72
    • 31
    • 25
    • 7
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 60
    • 12
    克隆类型
    • 52
    • 20
    多克隆
    标记
    • 46
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KAT2B antibody is un-conjugated
    应用范围
    • 56
    • 29
    • 16
    • 14
    • 13
    • 7
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    PCAF Antibody detects endogenous levels of total PCAF.
    预测反应
    Pig,Bovine,Horse,Sheep,Dog
    纯化方法
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    免疫原
    A synthesized peptide derived from human PCAF, corresponding to a region within C-terminal amino acids.
    亚型
    IgG
    Top Product
    Discover our top product KAT2B Primary Antibody
  • 应用备注
    WB: 1:500-1:3000, IHC: 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C. Stable for 12 months from date of receipt.
    有效期
    12 months
  • 抗原
    KAT2B (K(lysine) Acetyltransferase 2B (KAT2B))
    别名
    KAT2B (KAT2B 产品)
    别名
    PCAF antibody, pcaf antibody, si:ch211-1j13.2 antibody, zgc:161980 antibody, gb:dq017634 antibody, im:7156024 antibody, CAF antibody, P antibody, P/CAF antibody, A930006P13Rik antibody, AI461839 antibody, AW536563 antibody, Pcaf antibody, p/CAF antibody, lysine acetyltransferase 2B antibody, K(lysine) acetyltransferase 2B antibody, K(lysine) acetyltransferase 2A antibody, KAT2B antibody, kat2b antibody, kat2a antibody, Kat2b antibody
    背景

    Description: Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Also acetylates non-histone proteins, such as ACLY, PLK4 and TBX5. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. Acts as a circadian transcriptional coactivator which enhances the activity of the circadian transcriptional activators: NPAS2-ARNTL/BMAL1 and CLOCK-ARNTL/BMAL1 heterodimers. Involved in heart and limb development by mediating acetylation of TBX5, acetylation regulating nucleocytoplasmic shuttling of TBX5 (PubMed:29174768). Acts as a negative regulator of centrosome amplification by mediating acetylation of PLK4 (PubMed:27796307).

    Gene: KAT2B

    分子量
    93kDa
    基因ID
    8850
    UniProt
    Q92831
    途径
    p53 Pathway, Regulation of Carbohydrate Metabolic Process
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