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NR2F6 抗体 (N-Term)

NR2F6 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN953750
发货至: 中国
  • 抗原 See all NR2F6 抗体
    NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
    抗原表位
    • 14
    • 8
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 24-53, N-Term
    适用
    • 53
    • 21
    • 21
    • 11
    • 8
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    宿主
    • 48
    • 4
    • 1
    克隆类型
    • 50
    • 3
    多克隆
    标记
    • 30
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NR2F6 antibody is un-conjugated
    应用范围
    • 34
    • 27
    • 15
    • 6
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to NR2F6.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 24-53 amino acids from the N-terminal region of human NR2F6
    亚型
    Ig Fraction
    Top Product
    Discover our top product NR2F6 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
    别名
    NR2F6 (NR2F6 产品)
    别名
    EAR-2 antibody, EAR2 antibody, ERBAL2 antibody, AV090102 antibody, COUP-TF3 antibody, Erbal2 antibody, COUP(II) antibody, NR2F6 antibody, couptf2 antibody, fc94g11 antibody, wu:fc94g11 antibody, zgc:77259 antibody, ear-2 antibody, ear2 antibody, erbal2 antibody, nr2f6l antibody, wu:fc72d04 antibody, zgc:77260 antibody, nuclear receptor subfamily 2 group F member 6 antibody, nuclear receptor subfamily 2, group F, member 6 antibody, nuclear receptor subfamily 2, group F, member 6a antibody, nuclear receptor subfamily 2 group F member 6 L homeolog antibody, nuclear receptor subfamily 2, group F, member 6b antibody, NR2F6 antibody, Nr2f6 antibody, nr2f6a antibody, nr2f6.L antibody, nr2f6 antibody, nr2f6b antibody
    背景
    Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock, is required early in the development of the locus coeruleus (LC).Synonyms: EAR2, ERBAL2, Nuclear receptor subfamily 2 group F member 6, Orphan nuclear receptor EAR-2, V-erbA-related protein EAR-2
    分子量
    42979 Da
    基因ID
    2063
    NCBI登录号
    NP_005225
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism
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