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- 抗原 See all NR2F6 抗体
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NR2F6 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Chromatin Immunoprecipitation (ChIP)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to NR2F6 (nuclear receptor subfamily 2, group F, member 6)
NR2F6 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human NR2F6. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product NR2F6 Primary Antibody
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anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibody
NR2F6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 适用: 人, 小鼠, 大鼠, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (AA 6-194) antibodyNR2F6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (Ligand Binding Domain) antibodyNR2F6 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 斑马鱼, 猴, Bat, Hamster, 非洲爪蟾 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 适用: 人, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) antibodyNR2F6 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal EM-51 unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (N-Term) antibodyNR2F6 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig WB, IHC, IF, IP, IC 宿主: 兔 Polyclonal unconjugated
anti-Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6) (AA 11-60) antibodyNR2F6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- NR2F6 (Nuclear Receptor Subfamily 2, Group F, Member 6 (NR2F6))
- 别名
- nuclear receptor subfamily 2 group F member 6 (NR2F6 产品)
- 别名
- EAR-2 antibody, EAR2 antibody, ERBAL2 antibody, AV090102 antibody, COUP-TF3 antibody, Erbal2 antibody, COUP(II) antibody, NR2F6 antibody, couptf2 antibody, fc94g11 antibody, wu:fc94g11 antibody, zgc:77259 antibody, ear-2 antibody, ear2 antibody, erbal2 antibody, nr2f6l antibody, wu:fc72d04 antibody, zgc:77260 antibody, nuclear receptor subfamily 2 group F member 6 antibody, nuclear receptor subfamily 2, group F, member 6 antibody, nuclear receptor subfamily 2, group F, member 6a antibody, nuclear receptor subfamily 2 group F member 6 L homeolog antibody, nuclear receptor subfamily 2, group F, member 6b antibody, NR2F6 antibody, Nr2f6 antibody, nr2f6a antibody, nr2f6.L antibody, nr2f6 antibody, nr2f6b antibody
- 背景
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Transcription factor predominantly involved in transcriptional repression. Binds to promoter/enhancer response elements that contain the imperfect 5'-AGGTCA-3' direct or inverted repeats with various spacings which are also recognized by other nuclear hormone receptors. Involved in modulation of hormonal responses. Represses transcriptional activity of the lutropin-choriogonadotropic hormone receptor/LHCGR gene, the renin/REN gene and the oxytocin-neurophysin/OXT gene. Represses the triiodothyronine-dependent and -independent transcriptional activity of the thyroid hormone receptor gene in a cell type-specific manner. The corepressing function towards thyroid hormone receptor beta/THRB involves at least in part the inhibition of THRB binding to triiodothyronine response elements (TREs) by NR2F6. Inhibits NFATC transcription factor DNA binding and subsequently its transcriptional activity. Acts as transcriptional repressor of IL-17 expression in Th-17 differentiated CD4(+) T cells and may be involved in induction and/or maintenance of peripheral immunological tolerance and autoimmunity. Involved in development of forebrain circadian clock, is required early in the development of the locus coeruleus (LC).
Cellular Localization: Nucleus - 分子量
- 43 kDa
- 基因ID
- 2063
- UniProt
- P10588
- 途径
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Photoperiodism
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