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NR1H3 抗体 (Middle Region)

NR1H3 适用: 人 WB, FACS, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN953747
发货至: 中国
  • 抗原 See all NR1H3 抗体
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    抗原表位
    • 16
    • 15
    • 8
    • 8
    • 7
    • 6
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 232-262, Middle Region
    适用
    • 76
    • 56
    • 45
    • 17
    • 8
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    • 5
    • 5
    • 3
    • 3
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    • 3
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    • 1
    • 1
    • 1
    • 1
    宿主
    • 84
    • 9
    • 2
    克隆类型
    • 77
    • 18
    多克隆
    标记
    • 43
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This NR1H3 antibody is un-conjugated
    应用范围
    • 81
    • 31
    • 27
    • 27
    • 26
    • 10
    • 10
    • 8
    • 8
    • 7
    • 6
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Enzyme Immunoassay (EIA)
    特异性
    This antibody reacts to NR1H3.
    交叉反应 (详细)
    Species reactivity (tested):Human.
    纯化方法
    Affinity chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 232~262 amino acids from the Central region of human NR1H3
    亚型
    Ig Fraction
    Top Product
    Discover our top product NR1H3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % (W/V) sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    别名
    NR1H3 (NR1H3 产品)
    别名
    NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
    背景
    NR1H3 form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs, see MIM 180245) and regulate expression of target genes containing LXR response elements.Synonyms: LXRA, Liver X receptor alpha, Nuclear orphan receptor LXR-alpha, Nuclear receptor subfamily 1 group H member 3, Oxysterols receptor LXR-alpha
    分子量
    50396 Da
    基因ID
    10062
    NCBI登录号
    NP_001123573
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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