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NR1H3 抗体 (AA 1-402)

NR1H3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7162411
发货至: 中国
  • 抗原 See all NR1H3 抗体
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    抗原表位
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    AA 1-402
    适用
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    宿主
    • 84
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    克隆类型
    • 77
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    多克隆
    标记
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    This NR1H3 antibody is un-conjugated
    应用范围
    • 81
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    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    人, 小鼠
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Oxysterols receptor LXR-alpha protein (1-402AA)
    亚型
    IgG
    Top Product
    Discover our top product NR1H3 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    NR1H3 (Nuclear Receptor Subfamily 1, Group H, Member 3 (NR1H3))
    别名
    NR1H3 (NR1H3 产品)
    别名
    NR1H3 antibody, LXR-a antibody, LXRA antibody, RLD-1 antibody, AU018371 antibody, LXR antibody, RLD1 antibody, Unr1 antibody, LXRalpha antibody, LXR-alpha antibody, im:7141239 antibody, wu:fd59b01 antibody, zgc:113339 antibody, zgc:158542 antibody, nuclear receptor subfamily 1 group H member 3 antibody, nuclear receptor subfamily 1, group H, member 3 antibody, NR1H3 antibody, nr1h3 antibody, Nr1h3 antibody
    背景

    Background: Nuclear receptor that exhibits a ligand-dependent transcriptional activation activity (PubMed:19481530, PubMed:25661920). Interaction with retinoic acid receptor (RXR) shifts RXR from its role as a silent DNA-binding partner to an active ligand-binding subunit in mediating retinoid responses through target genes defined by LXRES (By similarity). LXRES are DR4-type response elements characterized by direct repeats of two similar hexanuclotide half-sites spaced by four nucleotides (By similarity). Plays an important role in the regulation of cholesterol homeostasis, regulating cholesterol uptake through MYLIP-dependent ubiquitination of LDLR, VLDLR and LRP8 (PubMed:19481530). Interplays functionally with RORA for the regulation of genes involved in liver metabolism (By similarity).

    Aliases: Liver X receptor alpha antibody, LXR a antibody, LXRA antibody, NR1H3 antibody, NR1H3_HUMAN antibody, Nuclear receptor subfamily 1 group H member 3 antibody, Oxysterols receptor LXR alpha antibody, Oxysterols receptor LXR-alpha antibody, RLD 1 antibody, RLD1 antibody

    UniProt
    Q13133
    途径
    Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Nuclear Hormone Receptor Binding, Cellular Response to Molecule of Bacterial Origin, Hepatitis C
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