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DFFA 抗体 (C-Term)

DFFA 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951895
发货至: 中国
  • 抗原 See all DFFA 抗体
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    抗原表位
    • 15
    • 13
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 302-331, C-Term
    适用
    • 73
    • 33
    • 20
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 75
    • 9
    • 1
    克隆类型
    • 77
    • 8
    多克隆
    标记
    • 61
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DFFA antibody is un-conjugated
    应用范围
    • 82
    • 30
    • 15
    • 14
    • 13
    • 13
    • 12
    • 10
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody recognizes Human DFFA / ICAD (C-term).
    纯化方法
    Affinity Chromatography on Protein A
    免疫原
    KLH conjugated synthetic peptide between 302~331 amino acids from the C-terminal region of Human DFFA / ICAD. Genename: DFFA
    亚型
    Ig Fraction
    Top Product
    Discover our top product DFFA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.25 mg/mL
    缓冲液
    PBS, 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    DFFA (DNA Fragmentation Factor, 45kDa, alpha Polypeptide (DFFA))
    别名
    DFFA / ICAD (DFFA 产品)
    别名
    DFF-45 antibody, DFF1 antibody, ICAD antibody, A330085O09Rik antibody, DFF35 antibody, Dff45 antibody, ICAD-L antibody, ICAD-S antibody, DFFA antibody, zgc:92229 antibody, DNA fragmentation factor subunit alpha antibody, DNA fragmentation factor, alpha subunit antibody, DNA fragmentation factor, 45kDa, alpha polypeptide antibody, DNA fragmentation factor, alpha polypeptide antibody, DFFA antibody, Dffa antibody, dffa antibody
    背景
    DFFA is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis.Synonyms: DFF-45, DFF1, DFF45, DNA fragmentation factor 45 kDa subunit, DNA fragmentation factor subunit alpha, Inhibitor of CAD
    分子量
    36522 Da
    基因ID
    1676
    NCBI登录号
    NP_004392
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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