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CD80 抗体

CD80 适用: 小鼠 FACS 宿主: 大鼠 Monoclonal RMMP-1 unconjugated
产品编号 ABIN951413
发货至: 中国
  • 抗原 See all CD80 抗体
    CD80
    适用
    • 131
    • 95
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    小鼠
    宿主
    • 87
    • 63
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    大鼠
    克隆类型
    • 117
    • 77
    • 2
    单克隆
    标记
    • 83
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    This CD80 antibody is un-conjugated
    应用范围
    • 114
    • 91
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    Flow Cytometry (FACS)
    特异性
    This antibody recognises the murine CD80 cell surface protein, also known as B7-1.
    交叉反应 (详细)
    Species reactivity (tested):Mouse.
    纯化方法
    Purified
    克隆位点
    RMMP-1
    亚型
    IgG2a
    Top Product
    Discover our top product CD80 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.1 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative and EIA grade BSA to bring total protein concentration to 4-5 mg/mL
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    DO NOT FREEZE! This product is photosensitive and should be protected from light.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    CD80
    别名
    CD80 (CD80 产品)
    别名
    B7 antibody, B7-1 antibody, B7.1 antibody, BB1 antibody, CD28LG antibody, CD28LG1 antibody, LAB7 antibody, B71 antibody, Cd28l antibody, Ly-53 antibody, Ly53 antibody, MIC17 antibody, TSA1 antibody, CD80 molecule antibody, Cd80 molecule antibody, CD80 antigen antibody, CD80 antibody, Cd80 antibody
    背景
    CD80 is a member of the Ig superfamily, along with CD86 (B7-2), participates in T cell costimulation via interactions with CD28 and CTLA-4. CD80 is constitutively expressed on dendritic cells, monocytes, and peritoneal macrophages, and it is inducible on B cells by various means, including activation by LPS, IL-4, and the cross-linking of surface Ig. Expression of CD80 is greatly enhanced on splenic B cells following activation by LPS, with peak expression occurring between 48 and 72 hours. It has been reported that activation of purified B cells with LPS can induce CD80 expression in as few as 18 hours.Synonyms: Activation B7-1 antigen, B7-1, B7.1, BB1, CD28LG, CD28LG1, CTLA-4 counter-receptor B7.1, LAB7, T-lymphocyte activation antigen CD80
    基因ID
    12519
    NCBI登录号
    NP_033985
    UniProt
    Q00609
    途径
    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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