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TLR4 抗体 (N-Term)

TLR4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN951277
发货至: 中国
  • 抗原 See all TLR4 抗体
    TLR4 (Toll-Like Receptor 4 (TLR4))
    抗原表位
    • 16
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    N-Term
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This TLR4 antibody is un-conjugated
    应用范围
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    Western Blotting (WB), Immunofluorescence (IF)
    纯化方法
    Purified
    免疫原
    Peptide corresponding to 15 amino acids near the amino-terminus of human TLR4
    亚型
    IgG
    Top Product
    Discover our top product TLR4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.
  • 抗原
    TLR4 (Toll-Like Receptor 4 (TLR4))
    别名
    CD284 / TLR4 (TLR4 产品)
    别名
    ARMD10 antibody, CD284 antibody, TLR-4 antibody, TOLL antibody, Lps antibody, Ly87 antibody, Ran/M1 antibody, Rasl2-8 antibody, toll like receptor 4 antibody, toll-like receptor 4 antibody, TLR4 antibody, Tlr4 antibody
    背景
    Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) α/β and NF-κB (4-6). Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis (7). TLR4 is located in the membrane and highly expressed in placenta, spleen and peripheral blood leukocytes. Detected in monocytes, macrophages, dendritic cells and several types of T-cells (8).Synonyms: Toll-like receptor 4
    NCBI登录号
    NM_138554
    UniProt
    O00206
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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