Insulin 抗体
(2 references)Quick Overview for Insulin 抗体 (ABIN94408)
抗原
See all Insulin (INS) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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原理
- Anti-Insulin Purified
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特异性
- The antibody IN-05 reacts with insulin, one of the major regulatory endocrine hormones of intermediate metabolism, normally secreted by the beta cells (a type of islet cells) of the pancreas, it is also present in tumors of B cell origin such as insulinoma.
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交叉反应 （详细）
- Human, Bovine, Porcine
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纯化方法
- Purified by protein-A affinity chromatography.
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纯度
- > 95 % (by SDS-PAGE)
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免疫原
- Porcine insulin.
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亚型
- IgG1
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anti-Insulin (INS) (AA 1-110) antibody
INS 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 46-59) antibodyINS 适用: 小鼠, 大鼠 WB, ELISA, IHC (p), FACS, IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人 IHC, WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Insulin (INS) (AA 90-110) antibodyINS 适用: 小鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 大鼠 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人, Pig, 小鼠, Cow, 大鼠, 兔, 豚鼠, 犬, 猴, Avian, 绵羊, 马, Hamster, 山羊, 驴, 小鸡, Cat WB 宿主: 山羊 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) (AA 25-110) antibodyINS 适用: 人 IHC, WB, IP, ICC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-Insulin (INS) (AA 25-54) antibodyINS 适用: Cow IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Insulin (INS) antibodyINS 适用: 人 IHC, ELISA 宿主: 兔 Monoclonal 1F6 unconjugated Recombinant Antibody
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Do not freeze.
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储存条件
- 4 °C
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储存方法
- Store at 2-8°C. Do not freeze.
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: "Biopolymer-coated gold nanoparticles inhibit human insulin amyloid fibrillation." in: Scientific reports, Vol. 10, Issue 1, pp. 7862, (2020) (PubMed).
: "Murine hybridoma monoclonal antibodies against insulin: cross-reactivity with insulins of three species and blocking of insulin binding to its receptor." in: Immunology letters, Vol. 8, Issue 5, pp. 279-83, (1985) (PubMed).
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: "Biopolymer-coated gold nanoparticles inhibit human insulin amyloid fibrillation." in: Scientific reports, Vol. 10, Issue 1, pp. 7862, (2020) (PubMed).
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- Insulin (INS)
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别名
- Insulin
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背景
- Proinsulin,Insulin and glucagon are pancreatic endocrine hormones secreted by islet cells within the pancreas. The stimulus for insulin secretion is a HIGH blood glucose. Deficiency of insulin results in diabetes mellitus, one of the leading causes of morbidity and mortality in the general population.,IDDM, INS
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基因ID
- 3630
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UniProt
- P01308
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途径
- NF-kappaB Signaling, RTK signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
抗原
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