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CHEK2 抗体 (N-Term)

This anti-CHEK2 antibody is a 兔多克隆 antibody detecting CHEK2 in WB. Suitable for 人.

产品编号 ABIN927287

发货至: 中国

Quick Overview for CHEK2 抗体 (N-Term) (ABIN927287)

抗原

See all CHEK2 抗体

CHEK2 (Checkpoint Kinase 2 (CHEK2))

适用

237
86
72
16
13
7
6
5
3
2
2
1

人

宿主

兔

克隆类型

多克隆

标记

111
11
9
9
7
7
7
7
7
7
7
7
7
7
7
3
3
3
3
3
3
2
2
1

This CHEK2 antibody is un-conjugated

应用范围

202
79
78
69
41
38
32
28
24
20
18
5
1
1
1
1
1

Western Blotting (WB)

Discover our top product CHEK2 Primary Antibody

抗原表位
26

25

19

17

16

16

15

15

9

8

8

8

6

4

3

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
N-Term

纯化方法

Purified

免疫原

CHEK2 antibody was raised in rabbit using the N terminal of CHEK2 as the immunogen
anti-Checkpoint Kinase 2 (CHEK2) (pThr387) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-543) antibody
CHEK2 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 4B7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pSer516) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr68) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (pThr383) antibody
CHEK2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 适用: 人, 犬 WB, IHC, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 2H5 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 适用: 人, 犬 WB, IHC, IF, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 5C4 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) antibody
CHEK2 适用: 人, 猴, 犬 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 10G7 unconjugated

anti-Checkpoint Kinase 2 (CHEK2) (AA 1-220) antibody
CHEK2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

说明

CHEK2 Blocking Peptide, (ABIN5612844), is also available for use as a blocking control in assays to test for specificity of this CHEK2 antibody

限制

仅限研究用
状态

Lyophilized

浓度

Lot specific

缓冲液

Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

注意事项

Avoid repeated freeze/thaw cycles.

储存条件

4 °C/-20 °C

储存方法

Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
抗原

CHEK2 (Checkpoint Kinase 2 (CHEK2))

别名

CHEK2

背景

In response to DNA damage and replication blocks, cell cycle progression is halted through the control of critical cell cycle regulators. CHEK2 is a cell cycle checkpoint regulator and putative tumor suppressor. It contains a forkhead-associated protein interaction domain essential for activation in response to DNA damage and is rapidly phosphorylated in response to replication blocks and DNA damage. When activated, CHEK2 is known to inhibit CDC25C phosphatase, preventing entry into mitosis, and has been shown to stabilize the tumor suppressor protein p53, leading to cell cycle arrest in G1. In addition, this protein interacts with and phosphorylates BRCA1, allowing BRCA1 to restore survival after DNA damage. Synonyms: Polyclonal CHEK2 antibody, Anti-CHEK2 antibody, CHK2 checkpoint homolog, S. pombe antibody, RP11-436C9.1 antibody, CDS1 antibody, CHK2 antibody, HuCds1 antibody, LFS2 antibody, PP1425 antibody, RAD53 antibody.

途径

p53 Pathway, Apoptosis, Cell Division Cycle

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