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SH2D1A 抗体 (C-Term)

SH2D1A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN926473
发货至: 中国
  • 抗原 See all SH2D1A 抗体
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    抗原表位
    • 14
    • 9
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 51
    • 19
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 47
    • 3
    • 1
    • 1
    克隆类型
    • 50
    • 2
    多克隆
    标记
    • 24
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH2D1A antibody is un-conjugated
    应用范围
    • 47
    • 20
    • 13
    • 4
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB)
    纯化方法
    Purified
    免疫原
    SH2 D2 antibody was raised in rabbit using the C terminal of SH2 2 as the immunogen
    Top Product
    Discover our top product SH2D1A Primary Antibody
  • 应用备注
    WB: 0.2-1 µg/mL
    Optimal conditions should be determined by the investigator.
    说明

    SH2D1A Blocking Peptide, catalog no. 33R-10098, is also available for use as a blocking control in assays to test for specificity of this SH2D1A antibody

    限制
    仅限研究用
  • 状态
    Lyophilized
    浓度
    Lot specific
    缓冲液
    Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
    注意事项
    Avoid repeated freeze/thaw cycles.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
  • 抗原
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    别名
    SH2D1A (SH2D1A 产品)
    别名
    DSHP antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, XLP antibody, XLPD antibody, RGD1562408 antibody, Gm686 antibody, SH2D1A antibody, SH2 domain containing 1A antibody, SH2D1A antibody, Sh2d1a antibody
    背景
    SH2D1A is a protein that plays a major role in the bidirectional stimulation of T and B cells. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in SH2D1A gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Synonyms: Polyclonal SH2D1A antibody, Anti-SH2D1A antibody, SH2 domain protein 1A antibody, DSHP antibody, EBVS antibody, FLJ18687 antibody, FLJ92177 antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, XLP antibody, XLPD antibody.
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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