SH2D1A 抗体 (C-Term)
-
- 抗原 See all SH2D1A 抗体
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SH2D1A antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 纯化方法
- Purified
- 免疫原
- SH2 D2 antibody was raised in rabbit using the C terminal of SH2 2 as the immunogen
- Top Product
- Discover our top product SH2D1A Primary Antibody
-
-
- 应用备注
-
WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator. - 说明
-
SH2D1A Blocking Peptide, catalog no. 33R-10098, is also available for use as a blocking control in assays to test for specificity of this SH2D1A antibody
- 限制
- 仅限研究用
-
- 状态
- Lyophilized
- 浓度
- Lot specific
- 缓冲液
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- 注意事项
- Avoid repeated freeze/thaw cycles.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
-
- 抗原
- SH2D1A (SH2 Domain Containing 1A (SH2D1A))
- 别名
- SH2D1A (SH2D1A 产品)
- 别名
- DSHP antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, XLP antibody, XLPD antibody, RGD1562408 antibody, Gm686 antibody, SH2D1A antibody, SH2 domain containing 1A antibody, SH2D1A antibody, Sh2d1a antibody
- 背景
- SH2D1A is a protein that plays a major role in the bidirectional stimulation of T and B cells. It associates with the signaling lymphocyte-activation molecule, thereby acting as an inhibitor of this transmembrane protein by blocking the recruitment of the SH2-domain-containing signal-transduction molecule SHP-2 to its docking site. This protein can also bind to other related surface molecules that are expressed on activated T, B and NK cells, thereby modifying signal transduction pathways in these cells. Mutations in SH2D1A gene cause lymphoproliferative syndrome X-linked type 1 or Duncan disease, a rare immunodeficiency characterized by extreme susceptibility to infection with Epstein-Barr virus, with symptoms including severe mononucleosis and malignant lymphoma. Synonyms: Polyclonal SH2D1A antibody, Anti-SH2D1A antibody, SH2 domain protein 1A antibody, DSHP antibody, EBVS antibody, FLJ18687 antibody, FLJ92177 antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, XLP antibody, XLPD antibody.
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
-