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SH2D1A 抗体 (AA 11-124)

SH2D1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7169449
发货至: 中国
  • 抗原 See all SH2D1A 抗体
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    抗原表位
    • 14
    • 9
    • 5
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 11-124
    适用
    • 50
    • 19
    • 19
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 46
    • 3
    • 1
    • 1
    克隆类型
    • 49
    • 2
    多克隆
    标记
    • 23
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SH2D1A antibody is un-conjugated
    应用范围
    • 47
    • 19
    • 13
    • 4
    • 4
    • 3
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human SH2 domain-containing protein 1A protein (11-124AA)
    亚型
    IgG
    Top Product
    Discover our top product SH2D1A Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    SH2D1A (SH2 Domain Containing 1A (SH2D1A))
    别名
    SH2D1A (SH2D1A 产品)
    别名
    DSHP antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, XLP antibody, XLPD antibody, RGD1562408 antibody, Gm686 antibody, SH2D1A antibody, SH2 domain containing 1A antibody, SH2D1A antibody, Sh2d1a antibody
    背景

    Background: Cytoplasmic adapter regulating receptors of the signaling lymphocytic activation molecule (SLAM) family such as SLAMF1, CD244, LY9, CD84, SLAMF6 and SLAMF7. In SLAM signaling seems to cooperate with SH2D1B/EAT-2. Initially it has been proposed that association with SLAMF1 prevents SLAMF1 binding to inhibitory effectors including INPP5D/SHIP1 and PTPN11/SHP-2 (PubMed:11806999). However, by simultaneous interactions, recruits FYN which subsequently phosphorylates and activates SLAMF1 (PubMed:12458214). Positively regulates CD244/2B4- and CD84-mediated natural killer (NK) cell functions. Can also promote CD48-, SLAMF6 -, LY9-, and SLAMF7-mediated NK cell activation. In the context of NK cell-mediated cytotoxicity enhances conjugate formation with target cells (By similarity). May also regulate the activity of the neurotrophin receptors NTRK1, NTRK2 and NTRK3.

    Aliases: DSHP antibody, Duncan disease SH2 protein antibody, Duncan disease SH2-protein antibody, EBVS antibody, IMD5 antibody, LYP antibody, MTCP1 antibody, SAP antibody, SAP/SH2D1A antibody, SH2 domain containing 1A antibody, SH2 domain protein 1A antibody, SH2 domain-containing protein 1A antibody, SH21A_HUMAN antibody, SH2D1A antibody, Signaling lymphocyte activation molecule associated protein antibody, Signaling lymphocytic activation molecule-associated protein antibody, SLAM associated protein antibody, SLAM associated protein/SH2 domain protein 1A antibody, SLAM-associated protein antibody, T cell signal transduction molecule SAP antibody, T-cell signal transduction molecule SAP antibody, XLP antibody, XLPD antibody

    UniProt
    O60880
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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