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TLR6 抗体 (Internal Region)

TLR6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN920626
发货至: 中国
  • 抗原 See all TLR6 抗体
    TLR6 (Toll-Like Receptor 6 (TLR6))
    抗原表位
    • 8
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    Internal Region
    适用
    • 60
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    • 2
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    宿主
    • 46
    • 16
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    克隆类型
    • 46
    • 17
    多克隆
    标记
    • 36
    • 8
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    This TLR6 antibody is un-conjugated
    应用范围
    • 37
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    • 8
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    Western Blotting (WB)
    产品特性
    Positive Control: Located in the membrane, TLR6 is detected in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells.
    纯化方法
    Antigen Immunoaffinity purified
    免疫原
    Rabbit polyclonal TLR6 antibody was raised against a peptide corresponding to 13 amino acids near the center of TLR6.
    亚型
    IgG
    Top Product
    Discover our top product TLR6 Primary Antibody
  • 应用备注
    Western blot: use at 0.5-1 µg/mL
    限制
    仅限研究用
  • 缓冲液
    Phosphate buffered saline with 0.02% sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
  • 抗原
    TLR6 (Toll-Like Receptor 6 (TLR6))
    Abstract
    TLR6 产品
    别名
    TLR1 antibody, TLR16 antibody, CD286 antibody, TLR-6 antibody, toll-like receptor 1 family member A antibody, toll like receptor 6 antibody, toll-like receptor 6 antibody, TLR1A antibody, TLR6 antibody, Tlr6 antibody
    背景
    Toll-like receptors (TRLs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors so the organism can respond to potential infection. TLR6 was first identified as a close homolog of TLR1, sharing 69% sequence identity. Like TLR1, TLR6 can form heterodimers with TLR2, and these TLR6:TLR2 heterodimers coordinate macrophage activation by Gram-positive bacteria and the yeast cell wall particle zymosan. Activation of these complexes not only initiates pro-inflammatory cascades, but can also lead to apoptotic responses. Synonyms:
    分子量
    96 kDa
    途径
    TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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