TIRAP 抗体 (AA 81-221) (Cy7)
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- 抗原 See all TIRAP 抗体
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
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抗原表位
- AA 81-221
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TIRAP antibody is conjugated to Cy7
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应用范围
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 预测反应
- Human,Mouse,Rat,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TIRAP
- 亚型
- IgG
- Top Product
- Discover our top product TIRAP Primary Antibody
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TIRAP (Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
- 别名
- TIRAP (TIRAP 产品)
- 别名
- mal antibody, wyatt antibody, BACTS1 antibody, Mal antibody, MyD88-2 antibody, AA407980 antibody, C130027E04Rik antibody, Tlr4ap antibody, Wyatt antibody, toll-interleukin 1 receptor (TIR) domain containing adaptor protein antibody, TIR domain containing adaptor protein antibody, toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog antibody, toll-interleukin 1 receptor (TIR) domain-containing adaptor protein antibody, tirap antibody, TIRAP antibody, tirap.L antibody, Tirap antibody
- 背景
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Synonyms: Toll/interleukin-1 receptor domain-containing adapter protein, TIR domain-containing adapter protein, Adaptor protein Wyatt, MyD88 adapter-like protein, MyD88-2, TIRAP, MAL
Background: Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6.
- 基因ID
- 114609
- 途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
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