TAP2 抗体 (AA 451-550) (Alexa Fluor 488)
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- 抗原 See all TAP2 抗体
- TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
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抗原表位
- AA 451-550
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAP2 antibody is conjugated to Alexa Fluor 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠
- 预测反应
- Rat,Dog,Cow,Pig,Horse,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human TAP2
- 亚型
- IgG
- Top Product
- Discover our top product TAP2 Primary Antibody
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anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 430-680) antibody
TAP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 451-550) antibodyTAP2 适用: 人, 小鼠 WB, ELISA, IF (p), IF (cc), FACS, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 100-134) antibodyTAP2 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB56970 unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 467-703) antibodyTAP2 适用: 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibodyTAP2 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 473-615) antibodyTAP2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibodyTAP2 适用: 人, 大鼠, 小鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 1-686) antibodyTAP2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) (AA 468-686) antibodyTAP2 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2) antibodyTAP2 适用: 人, 大鼠, 小鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
- 别名
- Tap2 (TAP2 产品)
- 别名
- ABC18 antibody, ABCB3 antibody, APT2 antibody, D6S217E antibody, PSF-2 antibody, PSF2 antibody, RING11 antibody, AI462429 antibody, Abcb3 antibody, Ham-2 antibody, Ham2 antibody, MTP2 antibody, Tap-2 antibody, Y1 antibody, jas antibody, Cim antibody, transporter 2, ATP binding cassette subfamily B member antibody, transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) antibody, TAP2 antibody, Tap2 antibody
- 背景
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Synonyms: Uncharacterized protein C9orf172, C9orf172
Background: TAP is an integral transmembrane protein involved in the transport of antigens from the cytoplasm to the endoplasmic reticulum for association with MHC class I molecules. It is a heterodimer of TAP1 and TAP2, and the peptide-binding site is shared between the cytoplasmic loops of TAP1 and TAP2. TAP is inducible by interferon gamma and belongs to the ABC transporter family, MDR subfamily. TAP also acts as a molecular scaffold for the final stage of MHC class I folding, namely the binding of peptide. Nascent MHC class I molecules associate with TAP via tapasin. TAP is inhibited by the covalent attachment of herpes simplex virus ICP47 protein, which blocks the peptide-binding site of TAP. It is inhibited by human cytomegalovirus US6 glycoprotein, which binds to the lumenal side of the TAP complex and inhibits peptide translocation by specifically blocking ATP-binding to TAP and prevents the conformational rearrangement of TAP induced by peptide binding.
- 基因ID
- 389813
- UniProt
- C9J069
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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