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TAP2 抗体 (AA 430-680)

TAP2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3022237
发货至: 中国
  • 抗原 See all TAP2 抗体
    TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
    抗原表位
    • 16
    • 15
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 430-680
    适用
    • 34
    • 19
    • 19
    宿主
    • 50
    克隆类型
    • 50
    多克隆
    标记
    • 13
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This TAP2 antibody is un-conjugated
    应用范围
    • 39
    • 26
    • 26
    • 16
    • 15
    • 9
    • 6
    • 6
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
    序列
    YGDMLSNVGA AEKVFSYMDR QPNLPSPGTL APTTLQGVVK FQDVSFAYPN RPDRPVLKGL TFTLRPGEVT ALVGPNGSGK STVAALLQNL YQPTGGQVLL DEKPISQYEH CYLHSQVVSV GQEPVLFSGS VRNNIAYGLQ SCEDDKVMAA AQAAHADDFI QEMEHGIYTD VGEKGSQLAA GQKQRLAIAR ALVRDPRVLI LDEATSALDV QCEQALQDWN SRGDRTVLVI AHRLQAVQRA HQILVLQEGK L
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Polyclonal Antibodies
    免疫原
    Recombinant fusion protein containing a sequence corresponding to amino acids 430-680 of human TAP2 (NP_000535.3).
    亚型
    IgG
  • 应用备注
    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid freeze / thaw cycles
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Avoid freeze / thaw cycles.
  • 抗原
    TAP2 (Transporter 2, ATP-Binding Cassette, Sub-Family B (MDR/TAP) (TAP2))
    别名
    TAP2 (TAP2 产品)
    别名
    ABC18 antibody, ABCB3 antibody, APT2 antibody, D6S217E antibody, PSF-2 antibody, PSF2 antibody, RING11 antibody, AI462429 antibody, Abcb3 antibody, Ham-2 antibody, Ham2 antibody, MTP2 antibody, Tap-2 antibody, Y1 antibody, jas antibody, Cim antibody, transporter 2, ATP binding cassette subfamily B member antibody, transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) antibody, TAP2 antibody, Tap2 antibody
    背景
    The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. This gene is located 7 kb telomeric to gene family member ABCB2. The protein encoded by this gene is involved in antigen presentation. This protein forms a heterodimer with ABCB2 in order to transport peptides from the cytoplasm to the endoplasmic reticulum. Mutations in this gene may be associated with ankylosing spondylitis, insulin-dependent diabetes mellitus, and celiac disease. Alternative splicing of this gene produces products which differ in peptide selectivity and level of restoration of surface expression of MHC class I molecules.,TAP2,ABC18,ABCB3,APT2,D6S217E,PSF-2,PSF2,RING11,Signal Transduction,TAP2
    分子量
    72 kDa/75 kDa
    基因ID
    6891
    UniProt
    Q03519
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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