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SHoc2/Sur8 抗体 (AA 36-120) (Alexa Fluor 350)

SHOC2 适用: 人, 小鼠, 大鼠 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN915169
发货至: 中国
  • 抗原 See all SHoc2/Sur8 (SHOC2) 抗体
    SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
    抗原表位
    • 14
    • 13
    • 10
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 36-120
    适用
    • 42
    • 27
    • 20
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 42
    克隆类型
    • 42
    多克隆
    标记
    • 15
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SHoc2/Sur8 antibody is conjugated to Alexa Fluor 350
    应用范围
    • 38
    • 19
    • 12
    • 12
    • 7
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    人, 小鼠, 大鼠
    预测反应
    Dog,Cow,Sheep,Chicken
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human SHOC2/Sur8
    亚型
    IgG
    Top Product
    Discover our top product SHOC2 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
    别名
    SHOC2 (SHOC2 产品)
    别名
    AU017287 antibody, Sur8 antibody, mKIAA0862 antibody, SIAA0862 antibody, SOC2 antibody, SUR8 antibody, si:ch211-159c12.3 antibody, si:ch211-197i12.3 antibody, zgc:152956 antibody, soc-2 (suppressor of clear) homolog (C. elegans) antibody, SHOC2 leucine-rich repeat scaffold protein antibody, SHOC2 leucine-rich repeat scaffold protein S homeolog antibody, SHOC2, leucine rich repeat scaffold protein antibody, Shoc2 antibody, shoc2.S antibody, SHOC2 antibody, shoc2 antibody
    背景

    Synonyms: Leucine-rich repeat protein SHOC-2, Leucine-rich repeat protein SHOC-2, Ras-binding protein Sur-8, KIAA0862, Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein Sur-8 homolog, SHOC2, SHOC2_HUMAN.

    Background: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.

    基因ID
    8036
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