SHoc2/Sur8 抗体 (AA 36-120)
-
- 抗原 See all SHoc2/Sur8 (SHOC2) 抗体
- SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
-
抗原表位
- AA 36-120
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This SHoc2/Sur8 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 小鼠, 大鼠
- 预测反应
- Dog,Cow,Sheep,Chicken
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human SHOC2/Sur8
- 亚型
- IgG
- Top Product
- Discover our top product SHOC2 Primary Antibody
-
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (AA 3-89) antibody
SHOC2 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (AA 455-562) antibodySHOC2 适用: 人 WB, IHC (p), IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (C-Term) antibodySHOC2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (AA 1-280) antibodySHOC2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (AA 56-83), (N-Term) antibodySHOC2 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB37466 unconjugated
anti-Leucine-rich repeat protein SHOC-2 (SHOC2) (N-Term) antibodySHOC2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
-
- 抗原
- SHoc2/Sur8 (SHOC2) (Leucine-rich repeat protein SHOC-2 (SHOC2))
- 别名
- SHOC2 (SHOC2 产品)
- 别名
- AU017287 antibody, Sur8 antibody, mKIAA0862 antibody, SIAA0862 antibody, SOC2 antibody, SUR8 antibody, si:ch211-159c12.3 antibody, si:ch211-197i12.3 antibody, zgc:152956 antibody, soc-2 (suppressor of clear) homolog (C. elegans) antibody, SHOC2 leucine-rich repeat scaffold protein antibody, SHOC2 leucine-rich repeat scaffold protein S homeolog antibody, SHOC2, leucine rich repeat scaffold protein antibody, Shoc2 antibody, shoc2.S antibody, SHOC2 antibody, shoc2 antibody
- 背景
-
Synonyms: Leucine-rich repeat protein SHOC-2, Leucine-rich repeat protein SHOC-2, Ras-binding protein Sur-8, KIAA0862, Leucine-rich repeat protein SHOC-2, Protein soc-2 homolog, Protein Sur-8 homolog, SHOC2, SHOC2_HUMAN.
Background: Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.Involvement in disease:Defects in SHOC2 are the cause of Noonan syndrome-like with loose anagen hair (NSLAH) . NSLAH children display macrocephaly, high forehead, hypertelorism, palpebral ptosis, low-set and posteriorly rotated ears, short and webbed neck and pectus anomalies. Affected subjects also have easily pluckable, sparse, thin and slow-growing hair.
- 基因ID
- 8036
-
