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SETD7 抗体 (AA 271-366) (Alexa Fluor 488)

SETD7 适用: 人 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488
产品编号 ABIN900896
发货至: 中国
  • 抗原 See all SETD7 抗体
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    抗原表位
    • 15
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 271-366
    适用
    • 63
    • 19
    • 10
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    宿主
    • 53
    • 9
    • 1
    克隆类型
    • 51
    • 11
    • 1
    多克隆
    标记
    • 31
    • 5
    • 4
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SETD7 antibody is conjugated to Alexa Fluor 488
    应用范围
    • 54
    • 28
    • 23
    • 17
    • 12
    • 12
    • 11
    • 11
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    预测反应
    Mouse,Rat,Dog,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human Histone H4 K4 methyltransferase SETD7
    亚型
    IgG
    Top Product
    Discover our top product SETD7 Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    SETD7 (SET Domain Containing (Lysine Methyltransferase) 7 (SETD7))
    别名
    H3-K4-HMTase SETD7 (SETD7 产品)
    别名
    KMT7 antibody, SET7 antibody, SET7/9 antibody, SET9 antibody, set7 antibody, zgc:101860 antibody, zgc:92330 antibody, 1600028F23Rik antibody, H3K4MT antibody, Set7 antibody, Set7/9 antibody, mKIAA1717 antibody, SET domain containing lysine methyltransferase 7 antibody, SET domain containing (lysine methyltransferase) 7 antibody, SETD7 antibody, setd7 antibody, Setd7 antibody
    背景

    Synonyms: FLJ21193, H3 K4 HMTase, H3-K4-HMTase SETD7, H4 lysine 4 specic, Histone H3 K4 methyltransferase, Histone H3 lysine 4 specic methyltransferase, Histone H3-K4 methyltransferase SETD7, Histone H4 K4 methyltransferase, Histone lysine N methyltransferase, Histone lysine N methyltransferase H3 lysine 4 specic SET7, Histone-lysine N-methyltransferase SETD7, KIAA1717, KMT7, Lysine methyltransferase, Lysine N-methyltransferase 7, OTTHUMP00000164543, OTTHUMP00000220049, SET 7, SET 7/9, SET 9, SET D7, SET domain containing lysine methyltransferase 7, SET domain containing protein 7, SET domain containing protein 8, SET domain-containing protein 7, SET7, SET7/9, SET9, Setd7, SETD7_HUMAN.

    Background: Histone methyltransferase that specifically monomethylates 'Lys-4' of histone H3. H3 'Lys-4' methylation represents a specific tag for epigenetic transcriptional activation. Plays a central role in the transcriptional activation of genes such as collagenase or insulin. Recruited by IPF1/PDX-1 to the insulin promoter, leading to activate transcription. Has also methyltransferase activity toward non-histone proteins such as p53/TP53, TAF10, and possibly TAF7 by recognizing and binding the [KR]-[STA]-K in substrate proteins. Monomethylates 'Lys-189' of TAF10, leading to increase the affinity of TAF10 for RNA polymerase II. Monomethylates 'Lys-372' of p53/TP53, stabilizing p53/TP53 and increasing p53/TP53-mediated transcriptional activation. Also able to demethylated 'Lys-372' of p53/TP53 in vitro.

    基因ID
    80854
    UniProt
    Q8WTS6
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