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DICER1 抗体 (AA 1301-1400) (Alexa Fluor 350)

DICER1 适用: 人 WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 350
产品编号 ABIN893989
发货至: 中国
  • 抗原 See all DICER1 抗体
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    抗原表位
    • 14
    • 11
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1301-1400
    适用
    • 45
    • 21
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 36
    • 22
    • 1
    克隆类型
    • 36
    • 23
    多克隆
    标记
    • 33
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DICER1 antibody is conjugated to Alexa Fluor 350
    应用范围
    • 48
    • 15
    • 14
    • 13
    • 13
    • 12
    • 12
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    交叉反应
    预测反应
    Mouse,Rat,Cow,Pig,Horse
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human DICER1
    亚型
    IgG
    Top Product
    Discover our top product DICER1 Primary Antibody
  • 应用备注
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
    别名
    DICER1 (DICER1 产品)
    别名
    dcr1 antibody, dicer antibody, herna antibody, DICER1 antibody, dicer1 antibody, 1110006F08Rik antibody, D12Ertd7e antibody, mKIAA0928 antibody, DCR1 antibody, Dicer antibody, HERNA antibody, MNG1 antibody, DICER antibody, fc39d11 antibody, fc74b05 antibody, wu:fc39d11 antibody, wu:fc74b05 antibody, dicer 1, ribonuclease III antibody, endoribonuclease Dicer antibody, dicer 1, ribonuclease III S homeolog antibody, dicer 1, ribonuclease type III antibody, dicer 1 ribonuclease III antibody, DICER1 antibody, CpipJ_CPIJ010534 antibody, dicer1 antibody, dicer1.S antibody, Dicer1 antibody
    背景

    Synonyms: DCR1, MNG1, Dicer, HERNA, RMSE2, Dicer1e, K12H4.8-LIKE, Endoribonuclease Dicer, Helicase with RNase motif, Helicase MOI, DICER1, KIAA0928

    Background: Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs serve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes.

    基因ID
    23405
    UniProt
    Q9UPY3
    途径
    Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization
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