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DICER1 抗体 (AA 1-195)

Name: DICER1 抗体 (AA 1-195)
SKU: ABIN3043347
Availability: OutOfStock

DICER1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western Blotting (WB) image for anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1-195) antibody (ABIN3043347) (DICER1 抗体 (AA 1-195))

Anti- Dicer antibody, IHC(P) IHC(P): Human Mammary Cancer Tissue (DICER1 抗体 (AA 1-195))

IHC

Anti- Dicer antibody, Western blotting All lanes: Anti Dicer at 0. (DICER1 抗体 (AA 1-195))

4 images

(2 references)

产品编号 ABIN3043347

发货至: 中国

Datasheet as PDF

抗原 See all DICER1 抗体

DICER1 (Dicer 1, Ribonuclease Type III (DICER1))
抗原表位
15

11

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1
AA 1-195
适用
48

22

6

1

1

1

1

1
人
宿主
38

23

1
兔
Compatible Secondaries
克隆类型
38

24
多克隆
标记
35

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This DICER1 antibody is un-conjugated
应用范围
50

17

16

13

13

13

13

7

5

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Endoribonuclease Dicer(DICER1) detection. Tested with WB, IHC-P in Human.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Endoribonuclease Dicer(DICER1) detection. Tested with WB, IHC-P in Human.
Gene Name: dicer 1, ribonuclease type III
Protein Name: Endoribonuclease Dicer

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Dicer recombinant protein (Position: M1-N195). Human Dicer shares 94% amino acid (aa) sequence identity with mouse Dicer.

亚型

IgG

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anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 6-290) antibody
DICER1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated

anti-Dicer 1, Ribonuclease Type III (DICER1) antibody
DICER1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Dicer 1, Ribonuclease Type III (DICER1) antibody
DICER1 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Monoclonal CL0378 unconjugated

anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody
DICER1 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S167-7 unconjugated

anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (HRP)
DICER1 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S167-7 HRP

anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (FITC)
DICER1 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S167-7 FITC

anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (Biotin)
DICER1 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S167-7 Biotin

anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (PE)
DICER1 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S167-7 PE

anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (APC)
DICER1 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S167-7 APC

anti-Dicer 1, Ribonuclease Type III (DICER1) (AA 1638-1899) antibody (PerCP)
DICER1 适用: 小鼠 WB, ICC, IF 宿主: 小鼠 Monoclonal S167-7 PerCP

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Dicer is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
Gao, Wang, Chen, Feng, Yang, Feng, Yang, Ye, Zhang: "Post-transcriptional modulation of protein phosphatase PPP2CA and tumor suppressor PTEN by endogenous siRNA cleaved from hairpin within PTEN mRNA 3'UTR in human liver cells." in: Acta pharmacologica Sinica, Vol. 37, Issue 7, pp. 898-907, (2017) (PubMed).

Gao, Wang, Feng, Feng, Zheng, Yang, Xiao, Lu, Ye, Zhang: "A hairpin within YAP mRNA 3'UTR functions in regulation at post-transcription level." in: Biochemical and biophysical research communications, Vol. 459, Issue 2, pp. 306-312, (2015) (PubMed).
抗原

DICER1 (Dicer 1, Ribonuclease Type III (DICER1))

别名

DICER1 (DICER1 产品)

别名

dcr1 antibody, dicer antibody, herna antibody, DICER1 antibody, dicer1 antibody, 1110006F08Rik antibody, D12Ertd7e antibody, mKIAA0928 antibody, DCR1 antibody, Dicer antibody, HERNA antibody, MNG1 antibody, DICER antibody, fc39d11 antibody, fc74b05 antibody, wu:fc39d11 antibody, wu:fc74b05 antibody, dicer 1, ribonuclease III antibody, endoribonuclease Dicer antibody, dicer 1, ribonuclease III S homeolog antibody, dicer 1, ribonuclease type III antibody, dicer 1 ribonuclease III antibody, DICER1 antibody, CpipJ_CPIJ010534 antibody, dicer1 antibody, dicer1.S antibody, Dicer1 antibody

背景

Dicer(DICER1), also known as endoribonuclease Dicer or helicase with RNase motif, is an enzyme that in humans is encoded by the DICER1 gene. It is mapped to 14q32.13. The DICER1 gene, a member of the ribonuclease III (RNaseIII) family, is involved in the generation of microRNAs (miRNAs), which modulate gene expression at the posttranscriptional level. DICER1 possesses an RNA helicase motif containing a DEXH box in its amino terminus and an RNA motif in the carboxy terminus DICER, also known as helicase-MOI, is required by the RNA interference and small temporal RNA (stRNA) pathways to produce the active small RNA component that represses gene expression. In addition, DICER1 is required for formation of the RNA induced silencing complex (RISC). It also cleaves double-stranded RNA to produce short interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs.

Synonyms: DCR antibody|DCR1 antibody|Dcr1 homolog (Drosophila) antibody|Dicer 1 antibody|Dicer 1 ribonuclease type III antibody|Dicer antibody|DICER_HUMAN antibody|Dicer1 antibody|Double-strand-specific ribonuclease antibody|Endoribonuclease Dicer antibody|Helicase moi antibody|Helicase with RNAse motif antibody|HERNA antibody|KIAA0928 antibody|MNG1 antibody|RMSE2 antibody

基因ID

23405

途径

Regulatory RNA Pathways, Stem Cell Maintenance, Ribonucleoprotein Complex Subunit Organization