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Cyclin D1 抗体 (AA 61-110) (Alexa Fluor 555)

Name: Cyclin D1 抗体 (AA 61-110) (Alexa Fluor 555)
SKU: ABIN892917
Availability: OutOfStock

CCND1 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 555

(1 reference)

产品编号 ABIN892917

发货至: 中国

Datasheet as PDF

抗原 See all Cyclin D1 (CCND1) 抗体

Cyclin D1 (CCND1)
抗原表位
22

21

16

15

13

10

9

7

7

7

7

7

6

6

5

5

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 61-110
适用
235

127

122

37

19

18

16

10

9

8

4

3

3

3

3

2

1

1

1

1

1
人, 小鼠, 大鼠, Cow, 兔, 绵羊
宿主
203

56

1
兔
Compatible Secondaries
克隆类型
192

66
多克隆
标记
117

28

21

9

7

7

7

7

7

7

6

4

3

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1
This Cyclin D1 antibody is conjugated to Alexa Fluor 555
应用范围
196

89

65

64

42

31

26

26

25

22

19

13

6

5

3

2

2

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

交叉反应

Cow, 人, 小鼠, 兔, 大鼠, 绵羊

预测反应

Dog

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse Cyclin D1

亚型

IgG

Top Product

Discover our top product CCND1 Primary Antibody
anti-Cyclin D1 (CCND1) (AA 61-110) antibody
CCND1 适用: 人, 小鼠, 大鼠, Cow, 兔, 绵羊 WB, ELISA, FACS, IHC (p), IF (cc), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D1 (CCND1) (C-Term) antibody
CCND1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D1 (CCND1) (AA 96-295) antibody
CCND1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D1 (CCND1) antibody
KO Validated CCND1 适用: 人 WB, IHC, IF, IP 宿主: 兔 Monoclonal unconjugated

anti-Cyclin D1 (CCND1) (AA 167-295) antibody
CCND1 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 3B6G3 unconjugated

anti-Cyclin D1 (CCND1) (AA 1-295) antibody
CCND1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 1F7F5 unconjugated

anti-Cyclin D1 (CCND1) (C-Term) antibody
CCND1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D1 (CCND1) (AA 68-97) antibody
CCND1 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB8066 unconjugated

anti-Cyclin D1 (CCND1) (AA 68-97) antibody
CCND1 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cyclin D1 (CCND1) antibody
CCND1 适用: 人, 小鼠, 大鼠, 猴 WB, IHC, FACS, IF, StM 宿主: 小鼠 Monoclonal DCS-6 unconjugated

应用备注

FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
Souza, Silva, Calloway, Kucuk, Rossi, McLemore: "Genistein protects hematopoietic stem cells against G-CSF-induced DNA damage." in: Cancer prevention research (Philadelphia, Pa.), Vol. 7, Issue 5, pp. 534-44, (2014) (PubMed).
抗原

Cyclin D1 (CCND1)

别名

Cyclin D1 (CCND1 产品)

别名

BCL1 antibody, D11S287E antibody, PRAD1 antibody, U21B31 antibody, AI327039 antibody, CycD1 antibody, Cyl-1 antibody, bcl-1 antibody, cD1 antibody, cb161 antibody, cycd1 antibody, etID37810.7 antibody, fb52e01 antibody, fc45c08 antibody, fc83a12 antibody, id:ibd1198 antibody, wu:fb52e01 antibody, wu:fc45c08 antibody, wu:fc83a12 antibody, ccnd1b antibody, prad1 antibody, ccnd1 antibody, ccnd1a antibody, bcl1 antibody, d11s287e antibody, u21b31 antibody, CCND1 antibody, cyclin D1 antibody, cyclin D1 S homeolog antibody, cyclin D1 L homeolog antibody, CCND1 antibody, Ccnd1 antibody, ccnd1 antibody, ccnd1.S antibody, ccnd1.L antibody

背景

Synonyms: cD1, CycD1, Cyl-1, PRAD1, bcl-1, AI32739, G1/S-specific cyclin-D1, Ccnd1
Background: Regulatory component of the cyclin D1-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also substrate for SMAD3, phosphorylating SMAD3 in a cell-cycle-dependent manner and repressing its transcriptional activity. Component of the ternary complex, cyclin D1/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex. Exhibits transcriptional corepressor activity with INSM1 on the NEUROD1 and INS promoters in a cell cycle-independent manner (By similarity).

基因ID

12443

UniProt

P25322

途径

PI3K-Akt Signaling, Cell Division Cycle, Mitotic G1-G1/S Phases, ER-Nucleus Signaling