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CD11b 抗体 (AA 77-180) (Alexa Fluor 488)

Name: CD11b 抗体 (AA 77-180) (Alexa Fluor 488)
SKU: ABIN888707
Availability: OutOfStock

ITGAM 适用: 人, 小鼠, 大鼠 FACS, WB, IF (cc), IF (p) 宿主: 兔 Polyclonal Alexa Fluor 488

(1 reference)

产品编号 ABIN888707

发货至: 中国

Datasheet as PDF

抗原 See all CD11b (ITGAM) 抗体

CD11b (ITGAM) (Integrin alpha M (ITGAM))
抗原表位
15

14

10

7

6

6

5

5

4

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 77-180
适用
250

159

61

33

17

17

16

14

11

7

7

5

5

2

2

1
人, 小鼠, 大鼠
宿主
132

101

95

4

1

1
兔
Compatible Secondaries
克隆类型
235

95

1
多克隆
标记
112

37

29

25

19

10

7

6

6

5

5

5

4

4

4

4

4

4

3

3

3

3

3

3

3

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1
This CD11b antibody is conjugated to Alexa Fluor 488
应用范围
247

80

76

70

56

36

36

25

20

19

12

12

7

6

5

5

4

3

2

2

2

1

1
Flow Cytometry (FACS), Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

特异性

The immunogen of this product has partial sequence similarity to CD11d and may cross react.

交叉反应

人, 小鼠, 大鼠

预测反应

Pig

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from human CD11b

亚型

IgG

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应用备注

FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
Oh, Lee, Ko, Ko, Kim, Wee: "Analysis of macrophage phenotype in rejected corneal allografts." in: Investigative ophthalmology & visual science, Vol. 54, Issue 12, pp. 7779-84, (2013) (PubMed).
抗原

CD11b (ITGAM) (Integrin alpha M (ITGAM))

别名

CD11b, CD11c (ITGAM 产品)

别名

CD11b/CD18 antibody, CR3 antibody, CR3A antibody, Cd11b antibody, F730045J24Rik antibody, Ly-40 antibody, MAC1 antibody, Mac-1 antibody, Mac-1a antibody, CD11B antibody, MAC-1 antibody, MAC1A antibody, MO1A antibody, SLEB6 antibody, C3bi antibody, integrin subunit alpha M antibody, integrin alpha M antibody, integrin, alpha M (complement component 3 receptor 3 subunit) antibody, integrin alpha-M antibody, ITGAM antibody, Itgam antibody, LOC100351865 antibody

背景

Synonyms: CR3A, MO1A, CD11B, MAC-1, MAC1A, SLEB6, Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor, ITGAM, Integrin alpha-X, ITGAX, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150,95 alpha chain, Leukocyte adhesion receptor p150,95, CD11c
Background: Integrin alpha-M/beta-2 is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. It is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b. Integrin alpha-M/beta-2 is also a receptor for fibrinogen, factor X and ICAM1. It recognizes P1 and P2 peptides of fibrinogen gamma chain.

基因ID

3684

UniProt

P11215

途径

Apoptosis, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation