BRE 抗体 (AA 301-383) (Alexa Fluor 488)
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- 抗原 See all BRE 抗体
- BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
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抗原表位
- AA 301-383
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BRE antibody is conjugated to Alexa Fluor 488
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应用范围
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Sheep,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human BRCC45
- 亚型
- IgG
- Top Product
- Discover our top product BRE Primary Antibody
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anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 51-229) antibody
BRE 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) antibodyKO Validated BRE 适用: 人 WB, IF, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 94-383) antibodyBRE 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (C-Term) antibodyBRE 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 9-338) antibodyBRE 适用: 人, 小鼠 WB, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (AA 1-415) antibodyBRE 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (C-Term) antibodyBRE 适用: 人, 小鼠, 大鼠, 豚鼠, 马, 兔, 斑马鱼, Cow, 犬, 非洲爪蟾, Bat, 小鸡, Hamster, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE) (N-Term) antibodyBRE 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- 有效期
- 12 months
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- 抗原
- BRE (Brain and Reproductive Organ-Expressed (TNFRSF1A Modulator) (BRE))
- 别名
- BRCC45 (BRE 产品)
- 别名
- brcc4 antibody, brcc45 antibody, BRE antibody, LOC100231620 antibody, BRCC4 antibody, BRCC45 antibody, 6030405P19Rik antibody, AI429776 antibody, B830038C02Rik antibody, im:7141046 antibody, zgc:110368 antibody, BRISC and BRCA1 A complex member 2 antibody, brain and reproductive organ-expressed (TNFRSF1A modulator) antibody, BRISC and BRCA1 A complex member 2 L homeolog antibody, babam2 antibody, BABAM2 antibody, Babam2 antibody, BRE antibody, babam2.L antibody
- 背景
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Synonyms: Brain and reproductive organ expressed TNFRSF1A modulator, BRCA1/BRCA2 containing complex subunit 4, BRCA1/BRCA2 containing complex subunit 45, BRCC4, BRCC45, BRE_HUMAN.
Background: BRCC45 was initially suggested to be a housekeeping protein that is highly expressed in brain and reproductive organs. Later experiments indicated BRCC45 forms a complex with the breast and ovarian predisposition proteins BRCA1 and BRCA2 as well as RAD51 and BRCC36. This complex has a ubiquitin E3 ligase activity and is thought to enhance cellular survival following DNA damage. BRCC45 has also been suggested to function as a death receptor associated anti apoptotic protein by inhibiting the BID induced activation of the mitochondrial apoptotic pathway. Higher levels of BRCC45 were detected in the majority of hepatocellular carcinomas, suggesting that BRCC45 may promote tumorigenesis when overexpressed. At least three isoforms of BRCC45 are known to exist.
- 基因ID
- 9577
- 途径
- Positive Regulation of Response to DNA Damage Stimulus
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