TNFRSF21 抗体 (AA 101-200)
(1 reference)-
- 抗原 See all TNFRSF21 抗体
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
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抗原表位
- AA 101-200
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适用
- 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TNFRSF21 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 小鼠, 大鼠
- 预测反应
- Human,Dog,Cow,Horse,Chicken,Rabbit
- 纯化方法
- Purified by Protein A.
- 免疫原
- KLH conjugated synthetic peptide derived from human DR6
- 亚型
- IgG
- Top Product
- Discover our top product TNFRSF21 Primary Antibody
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anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 406-605) antibody
TNFRSF21 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 356-385) antibodyTNFRSF21 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 371-655) antibodyTNFRSF21 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-56) antibodyTNFRSF21 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-655) antibodyTNFRSF21 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-472) antibodyTNFRSF21 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1B1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 372-665) antibodyTNFRSF21 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 42-335) antibodyTNFRSF21 适用: 人 FACS 宿主: 大鼠 Monoclonal Luke-1 unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-655) antibodyTNFRSF21 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) (AA 1-124) antibodyTNFRSF21 适用: 人 ELISA 宿主: 小鼠 Monoclonal 1B2 unconjugated
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- 应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500 - 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 μg/μL
- 缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- 有效期
- 12 months
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: "Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis." in: Nature, Vol. 536, Issue 7615, pp. 215-8, (2016) (PubMed).
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: "Tumour-cell-induced endothelial cell necroptosis via death receptor 6 promotes metastasis." in: Nature, Vol. 536, Issue 7615, pp. 215-8, (2016) (PubMed).
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- 抗原
- TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
- 别名
- DR6 (TNFRSF21 产品)
- 别名
- TNFRSF21 antibody, tnfrsf21 antibody, MGC146356 antibody, BM-018 antibody, CD358 antibody, DR6 antibody, AA959878 antibody, R74815 antibody, TR7 antibody, dr6 antibody, im:6795346 antibody, wu:fa55e01 antibody, wu:fb02e11 antibody, wu:fc29a09 antibody, wu:fi27h08 antibody, TNF receptor superfamily member 21 antibody, tumor necrosis factor receptor superfamily member 21 antibody, tumor necrosis factor receptor superfamily, member 21 antibody, TNFRSF21 antibody, tnfrsf21 antibody, Tnfrsf21 antibody
- 背景
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Synonyms: DR6, CD358, BM-018, Tumor necrosis factor receptor superfamily member 21, Death receptor 6, TNFRSF21, UNQ437/PRO868
Background: Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Plays a role in neuronal apoptosis, including apoptosis in response to amyloid peptides derived from APP, and is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21, this triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. Negatively regulates T-cell responses and the release of cytokines such as IL4, IL5, IL10, IL13 and IFNG by Th2 cells. Negatively regulates the production of IgG, IgM and IgM in response to antigens. May inhibit the activation of JNK in response to T-cell stimulation.
- 基因ID
- 27242
- UniProt
- O75509
- 途径
- Regulation of Lipid Metabolism by PPARalpha
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