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TNFRSF21 抗体 (AA 371-655)

TNFRSF21 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7173876
发货至: 中国
  • 抗原 See all TNFRSF21 抗体
    TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
    抗原表位
    • 9
    • 7
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 371-655
    适用
    • 57
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 45
    • 15
    • 2
    克隆类型
    • 47
    • 15
    多克隆
    标记
    • 39
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TNFRSF21 antibody is un-conjugated
    应用范围
    • 40
    • 30
    • 8
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Tumor necrosis factor receptor superfamily member 21 protein (371-655AA)
    亚型
    IgG
    Top Product
    Discover our top product TNFRSF21 Primary Antibody
  • 应用备注
    Recommended dilution: WB:1:200-1:1000, IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TNFRSF21 (Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21))
    别名
    TNFRSF21 (TNFRSF21 产品)
    别名
    TNFRSF21 antibody, tnfrsf21 antibody, MGC146356 antibody, BM-018 antibody, CD358 antibody, DR6 antibody, AA959878 antibody, R74815 antibody, TR7 antibody, dr6 antibody, im:6795346 antibody, wu:fa55e01 antibody, wu:fb02e11 antibody, wu:fc29a09 antibody, wu:fi27h08 antibody, TNF receptor superfamily member 21 antibody, tumor necrosis factor receptor superfamily member 21 antibody, tumor necrosis factor receptor superfamily, member 21 antibody, TNFRSF21 antibody, tnfrsf21 antibody, Tnfrsf21 antibody
    背景

    Background: Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Plays a role in neuronal apoptosis, including apoptosis in response to amyloid peptides derived from APP, and is required for both normal cell body death and axonal pruning. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). N-APP binds TNFRSF21, this triggers caspase activation and degeneration of both neuronal cell bodies (via caspase-3) and axons (via caspase-6). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation. Negatively regulates T-cell responses and the release of cytokines such as IL4, IL5, IL10, IL13 and IFNG by Th2 cells. Negatively regulates the production of IgG, IgM and IgM in response to antigens. May inhibit the activation of JNK in response to T-cell stimulation.

    Aliases: TNFRSF 21 antibody, BM 018 antibody, BM018 antibody, CD358 antibody, Death receptor 6 antibody, DR 6 antibody, DR6 antibody, MGC31965 antibody, OTTHUMP00000039915 antibody, TNFR related death receptor 6 antibody, TNFRSF21 antibody, TNFRSF21 protein antibody, TNR21_HUMAN antibody, Tumor necrosis factor receptor superfamily member 21 antibody, Tumor necrosis factor receptor superfamily member 21 precursor antibody

    UniProt
    O75509
    途径
    Regulation of Lipid Metabolism by PPARalpha
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