The antibody detects endogenous level of total N-Cadherin protein.
纯化方法
Affinity purified
免疫原
Peptide sequence around AA 800-804 (A-I-K-P-V) derived from Human N-Cadherin. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density