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EWSR1 抗体 (AA 213-217)

EWSR1 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN871485
发货至: 中国
  • 抗原 See all EWSR1 抗体
    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
    抗原表位
    • 13
    • 8
    • 7
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 213-217
    适用
    • 75
    • 35
    • 27
    • 10
    • 8
    • 8
    • 8
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    人, 小鼠, 大鼠
    宿主
    • 63
    • 10
    • 2
    • 1
    克隆类型
    • 66
    • 10
    多克隆
    标记
    • 53
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This EWSR1 antibody is un-conjugated
    应用范围
    • 67
    • 32
    • 15
    • 14
    • 7
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody detects endogenous levels of total EWS protein.
    纯化方法
    Affinity purified
    免疫原
    Peptide sequence around AA 213-217 (T-Y-G-Q-P) derived from Human EWS. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
    Top Product
    Discover our top product EWSR1 Primary Antibody
  • 应用备注
    Western blotting: 1:500-1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
  • 抗原
    EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))
    别名
    EWS (EWSR1 产品)
    别名
    EWS antibody, bK984G1.4 antibody, AU018891 antibody, Ews antibody, Ewsh antibody, EWSR1 antibody, fc04c01 antibody, wu:fc04c01 antibody, DKFZp459K1116 antibody, ewsr1 antibody, ewsr1.S antibody, fb40b11 antibody, fusl antibody, wu:fb40b11 antibody, wu:fb75g09 antibody, zgc:55864 antibody, EWS RNA binding protein 1 antibody, Ewing sarcoma breakpoint region 1 antibody, EWS RNA-binding protein 1 antibody, EWS RNA-binding protein 1a antibody, EWS RNA binding protein 1 L homeolog antibody, EWS RNA-binding protein 1b antibody, EWSR1 antibody, Ewsr1 antibody, ewsr1a antibody, ewsr1 antibody, ewsr1.L antibody, ewsr1b antibody
    背景
    This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
    分子量
    85 kDa
    基因ID
    2130
    NCBI登录号
    NP_053733
    UniProt
    Q9BZD1
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