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p53 抗体

This anti-p53 antibody is a 兔 多克隆 antibody detecting p53 in WB. Suitable for 人.
产品编号 ABIN866051
发货至: 中国
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中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for p53 抗体 (ABIN866051)

抗原

See all p53 (TP53) 抗体
p53 (TP53) (Tumor Protein P53 (TP53))

适用

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宿主

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克隆类型

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多克隆

标记

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This p53 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 特异性

    This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of N-terminal residues of p53.

    交叉反应

    人, 小鼠

    产品特性

    Positive Control: A431. Cellular Localization: Cytoplasm, nucleus

    纯化方法

    Immunogen affinity purified

    亚型

    IgG
  • 应用备注

    WB: 1:500-1,000

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5mg/ml

    缓冲液

    1xTBS (pH7.4), 0.5% BSA, 25% Glycerol

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    p53 (TP53) (Tumor Protein P53 (TP53))

    别名

    p53

    背景

    P53 is phosphorylated at multiple sites in vivo and by several different protein kinases in vitro. It acts as a tumor suppressor in many tumor types, induces growth arrest or apoptosis depending on the physiological circumstances and cell type. P53 is involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. p53 is frequently mutated or inactivated in about 60% of cancers

    分子量

    ~70kDa

    UniProt

    Q91XH8

    途径

    p53 Pathway, MAPK Pathway, PI3K-Akt Signaling, Apoptosis, AMPK Signaling, Chromatin Binding, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Autophagy, Warburg Effect
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