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NOTCH3 抗体 (C-Term)
NOTCH3
适用: 人, 小鼠, 大鼠
IHC (p), EIA
宿主: 山羊
Polyclonal
unconjugated
NOTCH3抗体详情
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抗原
See all NOTCH3 抗体
NOTCH3
(Notch 3 (NOTCH3))
抗原表位
All epitopes for NOTCH3 抗体
C-Term
适用
All reactivities for NOTCH3 抗体
人, 小鼠, 大鼠
宿主
All hosts for NOTCH3 抗体
山羊
克隆类型
All clonalities for NOTCH3 抗体
多克隆
标记
All conjugates for NOTCH3 抗体
This NOTCH3 antibody is un-conjugated
应用范围
All applications for NOTCH3 抗体
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
序列
C-QLGPQPEVTP KRQ
特异性
Recognizes NOTCH3
交叉反应 (详细)
Species reactivity (expected):Mouse, Rat. Species reactivity (tested):Human.
纯化方法
Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
免疫原
Peptide with sequence from the C Terminus of the protein sequence according to NP_000426.2.
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Alternatives
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使用细节
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应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
贮存及处理
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浓度
0.5 mg/mL
缓冲液
Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
NOTCH3目标详情
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抗原
NOTCH3
(Notch 3 (NOTCH3))
别名
NOTCH3 (NOTCH3 产品 )
别名
CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
背景
NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. It affects the implementation of differentiation, proliferation and apoptotic programs. Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).Synonyms: Neurogenic locus notch homolog protein 3, Notch-3
基因ID
4854
NCBI登录号
NP_000426
途径
Notch Signaling
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