电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NOTCH3 抗体 (C-Term)

NOTCH3 适用: 人, 小鼠, 大鼠 IHC (p), EIA 宿主: 山羊 Polyclonal unconjugated
产品编号 ABIN784287
发货至: 中国
  • 抗原 See all NOTCH3 抗体
    NOTCH3 (Notch 3 (NOTCH3))
    抗原表位
    • 14
    • 11
    • 7
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term
    适用
    • 50
    • 16
    • 11
    • 1
    人, 小鼠, 大鼠
    宿主
    • 34
    • 16
    • 2
    • 1
    • 1
    山羊
    克隆类型
    • 38
    • 17
    多克隆
    标记
    • 30
    • 5
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NOTCH3 antibody is un-conjugated
    应用范围
    • 27
    • 25
    • 22
    • 9
    • 7
    • 4
    • 3
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    序列
    C-QLGPQPEVTP KRQ
    特异性
    Recognizes NOTCH3
    交叉反应 (详细)
    Species reactivity (expected):Mouse, Rat.
    Species reactivity (tested):Human.
    纯化方法
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide
    免疫原
    Peptide with sequence from the C Terminus of the protein sequence according to NP_000426.2.
    Top Product
    Discover our top product NOTCH3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    0.5 mg/mL
    缓冲液
    Tris saline, pH ~7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    NOTCH3 (Notch 3 (NOTCH3))
    别名
    NOTCH3 (NOTCH3 产品)
    别名
    CADASIL antibody, CASIL antibody, IMF2 antibody, AW229011 antibody, N3 antibody, hpbk antibody, fa14b08 antibody, notch5 antibody, wu:fa14b08 antibody, notch 3 antibody, NOTCH3 antibody, Notch3 antibody, notch3 antibody
    背景
    NOTCH3 functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBP-J kappa and activates genes of the enhancer of split locus. It affects the implementation of differentiation, proliferation and apoptotic programs. Defects in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).Synonyms: Neurogenic locus notch homolog protein 3, Notch-3
    基因ID
    4854
    NCBI登录号
    NP_000426
    途径
    Notch Signaling
You are here:
客服