电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

NLRC3 抗体

NLRC3 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN784104
发货至: 中国
  • 抗原 See all NLRC3 抗体
    NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
    适用
    人, 小鼠, 大鼠
    宿主
    • 4
    • 1
    克隆类型
    • 4
    • 1
    多克隆
    标记
    • 5
    This NLRC3 antibody is un-conjugated
    应用范围
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    Human NLRC3
    交叉反应 (详细)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography.
    免疫原
    Synthetic peptide - KLH conjugated Remarks: Antigen Modification: Internal
    Top Product
    Discover our top product NLRC3 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % Sodium as preservative
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C
    储存方法
    Store the antibody undiluted at 2-8 °C.
  • 抗原
    NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
    别名
    NLRC3 (NLRC3 产品)
    别名
    NLRC3 antibody, nod3 antibody, NLR-A3 antibody, NOD3 antibody, CLR16.2 antibody, D230007K08Rik antibody, mFLJ00348 antibody, Nlrc3-ps1 antibody, RGD1304902 antibody, NLR family CARD domain containing 3 antibody, NLR family, CARD domain containing 3 antibody, NLRC3 antibody, nlrc3 antibody, Nlrc3 antibody
    背景
    NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-?B, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.Synonyms: CLR16.2, FLJ00348, NLRC3, NOD3
    基因ID
    197358
    NCBI登录号
    NP_849172
You are here:
客服