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- 抗原 See all NLRC3 抗体
- NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
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抗原表位
- Center
- 适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRC3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects NOD3 at Center.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 18 amino acid peptide near the center of human NOD3
- Top Product
- Discover our top product NLRC3 Primary Antibody
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anti-NLR Family, CARD Domain Containing 3 (NLRC3) (Internal Region) antibody
NLRC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
- 别名
- NOD3 (NLRC3 产品)
- 别名
- NLRC3 antibody, nod3 antibody, NLR-A3 antibody, NOD3 antibody, CLR16.2 antibody, D230007K08Rik antibody, mFLJ00348 antibody, Nlrc3-ps1 antibody, RGD1304902 antibody, NLR family CARD domain containing 3 antibody, NLR family, CARD domain containing 3 antibody, NLRC3 antibody, nlrc3 antibody, Nlrc3 antibody
- 背景
- NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-?B, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.Synonyms: CLR16.2, FLJ00348, NLRC3, NOD3
- 基因ID
- 197358
- NCBI登录号
- NP_849172
- UniProt
- Q7RTR2
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